O1571_RAT
ID O1571_RAT Reviewed; 249 AA.
AC P35899; Q9ERW9;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Olfactory receptor 1571;
DE AltName: Full=Putative gustatory receptor PTE58;
DE AltName: Full=Testis-expressed odorant receptor mT15r;
DE Flags: Fragment;
GN Name=Olr1571;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 1-232.
RC STRAIN=Fischer; TISSUE=Tongue epithelium;
RX PubMed=8380780; DOI=10.1016/0014-5793(93)81302-g;
RA Abe K., Kusakabe Y., Tanemura K., Emori Y., Arai S.;
RT "Multiple genes for G protein-coupled receptors and their expression in
RT lingual epithelia.";
RL FEBS Lett. 316:253-256(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 29-249.
RC STRAIN=Brown Norway;
RX PubMed=15057822; DOI=10.1038/nature02426;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA Mockrin S., Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into mammalian
RT evolution.";
RL Nature 428:493-521(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 80-212.
RC STRAIN=Sprague-Dawley;
RX PubMed=11014824; DOI=10.1093/genetics/156.2.785;
RA Branscomb A., Seger J., White R.L.;
RT "Evolution of odorant receptors expressed in mammalian testes.";
RL Genetics 156:785-797(2000).
CC -!- FUNCTION: Possible taste receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- TISSUE SPECIFICITY: Tongue specific.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AABR03081387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AF271052; AAG21325.1; -; Genomic_DNA.
DR PIR; S29001; S29001.
DR AlphaFoldDB; P35899; -.
DR SMR; P35899; -.
DR GlyGen; P35899; 1 site.
DR RGD; 1333684; Olr1571.
DR InParanoid; P35899; -.
DR PhylomeDB; P35899; -.
DR Proteomes; UP000002494; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN <1..249
FT /note="Olfactory receptor 1571"
FT /id="PRO_0000069671"
FT TRANSMEM <1..9
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 10..40
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..60
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 61..82
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 83..103
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 104..136
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..158
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 159..180
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..200
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 201..210
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..232
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 233..249
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 130
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 37..119
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
FT CONFLICT 231..232
FT /note="SL -> FF (in Ref. 1)"
FT /evidence="ECO:0000305"
FT NON_TER 1
SQ SEQUENCE 249 AA; 27711 MW; 309F985D8B229116 CRC64;
LLMCNLCFAD ICFTSASIPT NLVNIQTKNK VITYEGCISQ VYFFILFGVL DNFLLAVMAY
DRYVAICHPL HYTVIMNRRL CGLLVLGSWV TTALNSLLQS SMALRLSFCT DLKIPHFVCE
LNQLVLLACN DTFPNDMVMY FAAVLLGGGP LAGILYSYSK IVSSIRAISS SQGKYKAFST
CASHLSVVSL FYSTLLGVYL SSSFTQNSHS TARASVMYSV VTPMLNPFIY SLRNKDLMGA
LRRLFRRKP
