ARR24_ARATH
ID ARR24_ARATH Reviewed; 139 AA.
AC F4JZT3;
DT 25-APR-2018, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Two-component response regulator 24 {ECO:0000312|EMBL:AED93557.1};
DE AltName: Full=Arabidopsis response regulator 24 {ECO:0000303|PubMed:15356332};
GN Name=ARR24 {ECO:0000303|PubMed:15356332};
GN OrderedLocusNames=At5g26594 {ECO:0000312|Araport:AT5G26594};
GN ORFNames=T7I7 {ECO:0000305};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 18-130, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=15356332; DOI=10.1093/pcp/pch128;
RA Kiba T., Aoki K., Sakakibara H., Mizuno T.;
RT "Arabidopsis response regulator, ARR22, ectopic expression of which results
RT in phenotypes similar to the wol cytokinin-receptor mutant.";
RL Plant Cell Physiol. 45:1063-1077(2004).
RN [4]
RP DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Columbia, and cv. Wassilewskija;
RX PubMed=17099079; DOI=10.1093/jxb/erl205;
RA Gattolin S., Alandete-Saez M., Elliott K., Gonzalez-Carranza Z., Naomab E.,
RA Powell C., Roberts J.A.;
RT "Spatial and temporal expression of the response regulators ARR22 and ARR24
RT in Arabidopsis thaliana.";
RL J. Exp. Bot. 57:4225-4233(2006).
CC -!- FUNCTION: Functions as response regulator involved in His-to-Asp
CC phosphorelay signal transduction system. Phosphorylation of the Asp
CC residue in the receiver domain activates the ability of the protein to
CC promote the transcription of target genes. Type-A response regulators
CC seem to act as negative regulators of the cytokinin signaling.
CC {ECO:0000250|UniProtKB:Q9M8Y4}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9M8Y4}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in flowers and siliques, primarily
CC restricted to pollen grains. {ECO:0000269|PubMed:17099079}.
CC -!- DEVELOPMENTAL STAGE: In flowers, levels are reaching a maximum in buds
CC and open flowers before declining during pod development and
CC maturation. Strongly expressed in pollen grains within the anthers of
CC young and mature flowers. Occasionally present in the testa of
CC developing seeds. {ECO:0000269|PubMed:17099079}.
CC -!- PTM: Two-component system major event consists of a His-to-Asp
CC phosphorelay between a sensor histidine kinase (HK) and a response
CC regulator (RR). In plants, the His-to-Asp phosphorelay involves an
CC additional intermediate named Histidine-containing phosphotransfer
CC protein (HPt). This multistep phosphorelay consists of a His-Asp-His-
CC Asp sequential transfer of a phosphate group between first an His and
CC an Asp of the HK protein, followed by the transfer to a conserved His
CC of the HPt protein and finally the transfer to an Asp in the receiver
CC domain of the RR protein. {ECO:0000250|UniProtKB:Q9M8Y4}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:17099079}.
CC -!- SIMILARITY: Belongs to the ARR family. Type-A subfamily. {ECO:0000305}.
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DR EMBL; AC137518; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93557.1; -; Genomic_DNA.
DR RefSeq; NP_850864.1; NM_180533.1.
DR AlphaFoldDB; F4JZT3; -.
DR SMR; F4JZT3; -.
DR STRING; 3702.AT5G26594.1; -.
DR PaxDb; F4JZT3; -.
DR PRIDE; F4JZT3; -.
DR EnsemblPlants; AT5G26594.1; AT5G26594.1; AT5G26594.
DR GeneID; 832707; -.
DR Gramene; AT5G26594.1; AT5G26594.1; AT5G26594.
DR KEGG; ath:AT5G26594; -.
DR Araport; AT5G26594; -.
DR TAIR; locus:1005716875; AT5G26594.
DR eggNOG; KOG0519; Eukaryota.
DR HOGENOM; CLU_000445_69_12_1; -.
DR InParanoid; F4JZT3; -.
DR OMA; KPCLPQD; -.
DR OrthoDB; 1496846at2759; -.
DR PhylomeDB; F4JZT3; -.
DR PRO; PR:F4JZT3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4JZT3; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 2: Evidence at transcript level;
KW Cytokinin signaling pathway; Nucleus; Phosphoprotein; Reference proteome;
KW Transcription; Transcription regulation; Two-component regulatory system.
FT CHAIN 1..139
FT /note="Two-component response regulator 24"
FT /id="PRO_0000443959"
FT DOMAIN 19..134
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT MOD_RES 69
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 139 AA; 15575 MW; 938ADB3A76FB726B CRC64;
MTRDQVAEEL PNLAESKLTA LVVDDSFVNQ TIHQKLLNRL GIKNDVVTNG KEAVDVYCSG
GNYDLILMDM DMPIMNGIQA TKRLREMGIE SKIAGVTTRA NEGEKKEFME AGLNDFQEKP
LTISKLLSIL HKLNFYVQT
