ID   O1_VACCC                Reviewed;         666 AA.
AC   P21093;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   29-SEP-2021, entry version 64.
DE   RecName: Full=Protein O1;
GN   ORFNames=O1L;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae O1 family. {ECO:0000305}.
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DR   EMBL; M35027; AAA48053.1; -; Genomic_DNA.
DR   PIR; D42510; D42510.
DR   PRIDE; P21093; -.
DR   Proteomes; UP000008269; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR021155; Poxvirus_E2/O1.
DR   InterPro; IPR006732; Poxvirus_O1.
DR   Pfam; PF04497; Pox_E2-like; 2.
DR   PIRSF; PIRSF015980; VAC_O1L; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..666
FT                   /note="Protein O1"
FT                   /id="PRO_0000099638"
FT   TRANSMEM        574..596
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   666 AA;  77578 MW;  46DF3299DDEB66EF CRC64;
     MFMYPEFARK ALSKLISKKL NIEKVSSKHQ LVLLDYGLHG LLPKSLYLEA INSDILNVRF
     FPPEIINVTD IVKALQNSCR VDEYLKAVSL YHKNSLMVSG PNVVKLMIEY NLLTHSDLEW
     LINENVVKAT YLLKINAYMI NFKIDLTVDE IIDLVKDIPV GATLHLYNIL NNIDLDIVLR
     ISDEYNIPPV HDILSKLTDE EMCIKLVTKY PMDNVINFIN QDVRYSPTFI KTIKDFVNKH
     LPTMYDGLND YLHSVIIDED LIEEYKIKSV AMFNLEYKTD VDTLTLDEQI FVEVNISYYD
     FRYRQFADEF RDYIMIKERR QITMQSGDRI RRFRRPMSLR STIIKKDTDS LEDILAHIDN
     ARKNSKVSIE DVERIISSFR LNPCVVRRTM LSDIDIKTKI MVLKIVKDWK SCALTLSAIK
     GIMVTDTINT VLSKILHHHR NVFKYLTSVE NKEIAVCNCS RCLSLFYREL KSVRCDLRTD
     DGLLDRLYDL TRYALHGKIN QNLIGQRCWG PLTEMLFNEN KKKKLNNLME YIKISDMLVY
     GHSIEKTLIP ITDSLSFKLS VDTMSVLNDQ YAKIVIFFNT IIEYIIATIY YRLTVLNNYT
     NVKHFVSKVL HTVMEACGVL FSYIKVNDKI EHELEEMVDK GTVPSYLYHL SINVISIILD
     DINGTR