ID   O1_VACCW                Reviewed;         666 AA.
AC   Q80HX1;
DT   21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   02-JUN-2021, entry version 42.
DE   RecName: Full=Protein O1;
GN   OrderedLocusNames=VACWR068; ORFNames=O1L;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae O1 family. {ECO:0000305}.
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DR   EMBL; AY243312; AAO89347.1; -; Genomic_DNA.
DR   RefSeq; YP_232950.1; NC_006998.1.
DR   DNASU; 3707601; -.
DR   GeneID; 3707601; -.
DR   KEGG; vg:3707601; -.
DR   Proteomes; UP000000344; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR021155; Poxvirus_E2/O1.
DR   InterPro; IPR006732; Poxvirus_O1.
DR   Pfam; PF04497; Pox_E2-like; 2.
DR   PIRSF; PIRSF015980; VAC_O1L; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..666
FT                   /note="Protein O1"
FT                   /id="PRO_0000099639"
FT   TRANSMEM        574..596
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   666 AA;  77560 MW;  78E38BF39A14ED0F CRC64;
     MFMYPEFARK ALSKLISKKL NIEKVSSKHQ LVLLDYGLHG LLPKSLYLEA INSDILNVRF
     FPPEIINVTD IVKALQNSCR VDEYLKSVSL YHKNSLMVSG PNVVKLMIEY NLLTHSDLEW
     LINENVVKAT YLLKINAYMI NFKIDLTVDE IIDLVKDIPV GATLHLYNIL NNIDLDIVLR
     ISDEYNIPPV HDILSKLTDE EMCIKLVTKY PMDNVINFIN QDVRYSPTFI KTIKDFVNEH
     LPTMYDGLND YLHSVIIDED LIEEYKIKSV AMFNLEYKTD VNTLTLDEQI FVEVNISYYD
     FRYRQFADEF RDYIMIKERR QITMQSGDRI RRFRRPMSLR STIIKKDTDS LEDILAHIDN
     ARKNSKVSIE DVERIISSFR LNPCVVRRTM LSDIDIKTKI MVLKIVKDWK SCALTLSAIK
     GIMVTDTINT VLSKILHHHR NVFKYLTSVE NKEIAVCNCS RCLSLFYREL KSVRCDLHTD
     DGLLDRLYDL TRYALHGKIN QNLIGQRCWG PLTEMLFNEN KKKKLNNLME YIKISDMLVY
     GHSIEKTLIP ITDSLSFKLS VDTMSVLNDQ YAKVVIFFNT IIEYIIATIY YRLTVLNNYT
     NVKHFVSKVL HTVMEACGVL FSYIKVNDKI EHELEEMVDK GTVPSYLYHL SINVISIILD
     DINGTR