ID   O22R_FRG3G              Reviewed;         973 AA.
AC   Q6GZV3;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Putative helicase 022R;
DE            EC=3.6.4.-;
GN   ORFNames=FV3-022R;
OS   Frog virus 3 (isolate Goorha) (FV-3).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Pimascovirales; Iridoviridae; Alphairidovirinae; Ranavirus.
OX   NCBI_TaxID=654924;
OH   NCBI_TaxID=30343; Dryophytes versicolor (chameleon treefrog).
OH   NCBI_TaxID=8404; Lithobates pipiens (Northern leopard frog) (Rana pipiens).
OH   NCBI_TaxID=45438; Lithobates sylvaticus (Wood frog) (Rana sylvatica).
OH   NCBI_TaxID=8316; Notophthalmus viridescens (Eastern newt) (Triturus viridescens).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15165820; DOI=10.1016/j.virol.2004.02.019;
RA   Tan W.G., Barkman T.J., Gregory Chinchar V., Essani K.;
RT   "Comparative genomic analyses of frog virus 3, type species of the genus
RT   Ranavirus (family Iridoviridae).";
RL   Virology 323:70-84(2004).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY548484; AAT09681.1; -; Genomic_DNA.
DR   RefSeq; YP_031600.1; NC_005946.1.
DR   PRIDE; Q6GZV3; -.
DR   GeneID; 2947742; -.
DR   KEGG; vg:2947742; -.
DR   Proteomes; UP000008770; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR006500; DNA_primase_phage/plasmid.
DR   InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014818; Phage/plasmid_primase_P4_C.
DR   InterPro; IPR014819; PriCT_2.
DR   Pfam; PF08706; D5_N; 1.
DR   Pfam; PF08707; PriCT_2; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01613; primase_Cterm; 1.
DR   PROSITE; PS51206; SF3_HELICASE_1; 1.
PE   4: Predicted;
KW   ATP-binding; Hydrolase; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..973
FT                   /note="Putative helicase 022R"
FT                   /id="PRO_0000410581"
FT   DOMAIN          658..840
FT                   /note="SF3 helicase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00551"
FT   REGION          473..502
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         702..709
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00551"
SQ   SEQUENCE   973 AA;  108679 MW;  28C520FC8DC45260 CRC64;
     MANATIKYTT MDLYGILKSC KCSSDERLTH QSLSGGRFSV TGSKVGEFWR AVADRIESGE
     PIDISEARQK ETPLTLDFDV VDKDCKEPVP DVLVNNIHAA VARWARSSLK PAPEDRDLCG
     VVLTKPVRQC AKGWKKGFHI QYPKLVLETG VAKNLVVGPA LRPICSKVWE AVTGTAKDYL
     DPLSCTVPWL VYGASKPDEP FAWKIARTLD HAGKTIDFNT AFGDVETPPS WGRPTSDRHR
     EAMVLSIHPA GRSVFFRRYD FTAANPGRVT RLADYSAVMA KLDVARQRKP AWNTDATKAH
     RLKRVTDLTA MLTADLADDR QTWLNVGFCL WQQTSGSAEG YKVWLSFSKK SDKCDEDECW
     TIWNNQMRPN SFTEGTLVYL AQKHNPGAYL NWLQVKSTPV NDIGTNVAMA KIMWDYYGHQ
     FVCCGGKTQT WYRFDGLTWV ESNQGTDLRS LISAEGGPLR RLLMRQLDAV TAAKARGGRD
     SGNEDDEEDS ATDEDDSNPW DSELRRLDSE VLDTMVKRLR NNLKGIEMTG VKNNVLRECA
     ELFYQPEFGD VIDSDPLLFA FANGIYDFRE GCLRDGRPED KLSRRAPVDF VMFGPIPKAR
     HPDNSPVMRP KRMPGESVQD HARRLAECFE QDDVSASAGT MGKEDVESFS CNPNDFKGPV
     TKLLAFFASV FPDEGTRRFF LRNAAATFVG GNPDKVVLFW TGTGNNGKTV TQTLFEKMLG
     CFAVKMSTQT LTGRKPSAGS ANPEMARLGG GVRWAVMEEP NSDETINAGT LKSMTGNDSF
     FARDLYCAGK TTFEIKPMFK LHVICNALPG IKDADQATWN RVRVVPFEST FVTPGTTAPA
     DAKYVFPADT DITRKLDRLT APLAWYLVYC WACIQNERVK YVPPPKVMEA TMAYQKEHDL
     FRQFVEEMLR KDPDSTLTCD DAYTAFRDWT SANSPHGTVR RPKGQVVKCL EAILGKKTVD
     GWPGYAVGAE QQE