O3L5_ARATH
ID O3L5_ARATH Reviewed; 214 AA.
AC Q9SV19;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Protein OXIDATIVE STRESS 3 LIKE 5 {ECO:0000303|PubMed:18980652};
DE Short=AtO3L5 {ECO:0000303|PubMed:18980652};
DE AltName: Full=KID-containing protein-like 1 {ECO:0000303|PubMed:12631331};
DE Short=AtKCL1 {ECO:0000303|PubMed:12631331};
GN Name=O3L5 {ECO:0000303|PubMed:18980652};
GN Synonyms=KCL1 {ECO:0000303|PubMed:12631331};
GN OrderedLocusNames=At4g31510 {ECO:0000312|EMBL:AEE85922.1};
GN ORFNames=F3L17.80 {ECO:0000312|EMBL:CAB45910.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=12631331; DOI=10.1046/j.1365-313x.2003.01694.x;
RA Gao M.-J., Schaefer U.A., Parkin I.A.P., Hegedus D.D., Lydiate D.J.,
RA Hannoufa A.;
RT "A novel protein from Brassica napus has a putative KID domain and responds
RT to low temperature.";
RL Plant J. 33:1073-1086(2003).
RN [4]
RP FUNCTION, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Landsberg erecta, and cv. Wassilewskija;
RX PubMed=18980652; DOI=10.1111/j.1365-313x.2008.03717.x;
RA Blanvillain R., Kim J.H., Wu S., Lima A., Ow D.W.;
RT "OXIDATIVE STRESS 3 is a chromatin-associated factor involved in tolerance
RT to heavy metals and oxidative stress.";
RL Plant J. 57:654-665(2009).
CC -!- FUNCTION: Probable transcription factor (By similarity). Promotes
CC slightly the tolerance to cadmium (Cd) and zinc (Zn) and to oxidizing
CC chemicals (e.g. diamide and tert-butyl hydroperoxide (t-BOOH))
CC (PubMed:18980652). {ECO:0000250|UniProtKB:Q84U09,
CC ECO:0000269|PubMed:18980652}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
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DR EMBL; AL080283; CAB45910.1; -; Genomic_DNA.
DR EMBL; AL161579; CAB79869.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE85922.1; -; Genomic_DNA.
DR PIR; T10681; T10681.
DR RefSeq; NP_194879.1; NM_119300.3.
DR AlphaFoldDB; Q9SV19; -.
DR STRING; 3702.AT4G31510.1; -.
DR PaxDb; Q9SV19; -.
DR PRIDE; Q9SV19; -.
DR EnsemblPlants; AT4G31510.1; AT4G31510.1; AT4G31510.
DR GeneID; 829278; -.
DR Gramene; AT4G31510.1; AT4G31510.1; AT4G31510.
DR KEGG; ath:AT4G31510; -.
DR Araport; AT4G31510; -.
DR TAIR; locus:2125269; AT4G31510.
DR eggNOG; KOG4210; Eukaryota.
DR HOGENOM; CLU_066544_2_0_1; -.
DR InParanoid; Q9SV19; -.
DR OMA; SSFSIYT; -.
DR OrthoDB; 1263702at2759; -.
DR PhylomeDB; Q9SV19; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9SV19; baseline and differential.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR GO; GO:0046686; P:response to cadmium ion; IMP:UniProtKB.
DR GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR GO; GO:0010043; P:response to zinc ion; IMP:UniProtKB.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..214
FT /note="Protein OXIDATIVE STRESS 3 LIKE 5"
FT /id="PRO_0000455036"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..207
FT /note="Kinase-inducible domain (KID)"
FT /evidence="ECO:0000250|UniProtKB:Q84U09"
FT MOTIF 117..125
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT COMPBIAS 9..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 214 AA; 24001 MW; 8863E558EF299782 CRC64;
MEVLVGSTFR DRSSVTTHDQ AVPASLSSRI GLRRCGRSPP PESSSSVGET SENEEDEDDA
VSSSQGRWLN SFSSSLEDSL PIKRGLSNHY IGKSKSFGNL MEASNTNDLV KVESPLNKRR
RLLIANKLRR RSSLSSFSIY TKINPNSMPL LALQESDNED HKLNDDDDDD DSSSDDETSK
LKEKRMKMTN HRDFMVPQTK SCFSLTSFQD DDDR
