O3L6_ARATH
ID O3L6_ARATH Reviewed; 245 AA.
AC Q945P6; Q9SJB0;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Protein OXIDATIVE STRESS 3 LIKE 6 {ECO:0000303|PubMed:18980652};
DE Short=AtO3L6 {ECO:0000303|PubMed:18980652};
DE AltName: Full=KID-containing protein-like 2 {ECO:0000303|PubMed:12631331};
DE Short=AtKCL2 {ECO:0000303|PubMed:12631331};
GN Name=O3L6 {ECO:0000303|PubMed:18980652};
GN Synonyms=KCL2 {ECO:0000303|PubMed:12631331};
GN OrderedLocusNames=At2g24550 {ECO:0000312|Araport:AT2G24550};
GN ORFNames=F25P17.15 {ECO:0000312|EMBL:AAD23890.2};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=12631331; DOI=10.1046/j.1365-313x.2003.01694.x;
RA Gao M.-J., Schaefer U.A., Parkin I.A.P., Hegedus D.D., Lydiate D.J.,
RA Hannoufa A.;
RT "A novel protein from Brassica napus has a putative KID domain and responds
RT to low temperature.";
RL Plant J. 33:1073-1086(2003).
RN [5]
RP FUNCTION, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Landsberg erecta, and cv. Wassilewskija;
RX PubMed=18980652; DOI=10.1111/j.1365-313x.2008.03717.x;
RA Blanvillain R., Kim J.H., Wu S., Lima A., Ow D.W.;
RT "OXIDATIVE STRESS 3 is a chromatin-associated factor involved in tolerance
RT to heavy metals and oxidative stress.";
RL Plant J. 57:654-665(2009).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: Probable transcription factor (By similarity). Promotes
CC slightly the tolerance to cadmium (Cd) and to oxidizing chemicals (e.g.
CC diamide) (PubMed:18980652). {ECO:0000250|UniProtKB:Q84U09,
CC ECO:0000269|PubMed:18980652}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD23890.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006954; AAD23890.2; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC07591.1; -; Genomic_DNA.
DR EMBL; AF411794; AAL06484.1; -; mRNA.
DR EMBL; AY099874; AAM20725.1; -; mRNA.
DR EMBL; BT000317; AAN15636.1; -; mRNA.
DR PIR; A84638; A84638.
DR RefSeq; NP_565573.4; NM_128016.6.
DR AlphaFoldDB; Q945P6; -.
DR SMR; Q945P6; -.
DR IntAct; Q945P6; 9.
DR STRING; 3702.AT2G24550.1; -.
DR PaxDb; Q945P6; -.
DR PRIDE; Q945P6; -.
DR ProteomicsDB; 175720; -.
DR EnsemblPlants; AT2G24550.1; AT2G24550.1; AT2G24550.
DR GeneID; 816991; -.
DR Gramene; AT2G24550.1; AT2G24550.1; AT2G24550.
DR KEGG; ath:AT2G24550; -.
DR Araport; AT2G24550; -.
DR TAIR; locus:2046673; AT2G24550.
DR eggNOG; KOG4210; Eukaryota.
DR HOGENOM; CLU_066544_2_0_1; -.
DR InParanoid; Q945P6; -.
DR OMA; MNRKSPE; -.
DR OrthoDB; 1454473at2759; -.
DR PhylomeDB; Q945P6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q945P6; baseline and differential.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR GO; GO:0046686; P:response to cadmium ion; IMP:UniProtKB.
DR GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Stress response; Transcription;
KW Transcription regulation.
FT CHAIN 1..245
FT /note="Protein OXIDATIVE STRESS 3 LIKE 6"
FT /id="PRO_0000455037"
FT REGION 46..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 203..230
FT /note="Kinase-inducible domain (KID)"
FT /evidence="ECO:0000250|UniProtKB:Q84U09"
FT MOTIF 143..151
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
FT COMPBIAS 49..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 27247 MW; C70E64197C83C58F CRC64;
MEVMVGSSFG IGMAAYVRDH RGVSAQDKAV QTALFLADES GRGGSQIGIG LRMSNNNNKS
PEESSDSSSS IGESSENEEE EEEDDAVSCQ RGTLDSFSSS LEDSLPIKRG LSNHYVGKSK
SFGNLMEAAS KAKDLEKVEN PFNKRRRLVI ANKLRRRGRS MSASNFYSWQ NPNSMPLLAL
QEPNEEDHHI HNDDYEDDDG DGDDHRKIMM MMKNKKELMA QTRSCFCLSS LQEEDDGDGD
DDEDE
