OAC1_SCHPO
ID OAC1_SCHPO Reviewed; 320 AA.
AC Q9UTN1;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Mitochondrial oxaloacetate transport protein;
GN Name=oac1; ORFNames=SPAC139.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Transports oxaloacetate and sulfate. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane
CC protein.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAB59616.1; -; Genomic_DNA.
DR PIR; T37603; T37603.
DR RefSeq; NP_593169.1; NM_001018566.2.
DR AlphaFoldDB; Q9UTN1; -.
DR SMR; Q9UTN1; -.
DR BioGRID; 278282; 2.
DR STRING; 4896.SPAC139.02c.1; -.
DR iPTMnet; Q9UTN1; -.
DR MaxQB; Q9UTN1; -.
DR PaxDb; Q9UTN1; -.
DR PRIDE; Q9UTN1; -.
DR EnsemblFungi; SPAC139.02c.1; SPAC139.02c.1:pep; SPAC139.02c.
DR GeneID; 2541790; -.
DR KEGG; spo:SPAC139.02c; -.
DR PomBase; SPAC139.02c; oac1.
DR VEuPathDB; FungiDB:SPAC139.02c; -.
DR eggNOG; KOG0755; Eukaryota.
DR HOGENOM; CLU_015166_14_3_1; -.
DR InParanoid; Q9UTN1; -.
DR OMA; VMSRMYN; -.
DR PhylomeDB; Q9UTN1; -.
DR PRO; PR:Q9UTN1; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; ISS:PomBase.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0034658; F:isopropylmalate transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0015131; F:oxaloacetate transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0015117; F:thiosulfate transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1990556; P:mitochondrial isopropylmalate transmembrane transport; ISO:PomBase.
DR GO; GO:1990555; P:mitochondrial oxaloacetate transmembrane transport; ISO:PomBase.
DR GO; GO:1990557; P:mitochondrial sulfate transmembrane transport; ISO:PomBase.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..320
FT /note="Mitochondrial oxaloacetate transport protein"
FT /id="PRO_0000310788"
FT TRANSMEM 26..47
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..145
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 285..306
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 21..114
FT /note="Solcar 1"
FT REPEAT 126..218
FT /note="Solcar 2"
FT REPEAT 227..313
FT /note="Solcar 3"
SQ SEQUENCE 320 AA; 35548 MW; 72D629328913CF47 CRC64;
MSEKQTIKAL PAHNPTQVKK LGPVSGFLSG GLAACGAVTL TNPFEVIKTR FQLQGQLTKL
DPSKRIYKSV GQAFSLIARH EGIRGLQRGL GTAYVYQICL NGCRLGFYEP IRRTLNTWFL
DDPKGNKLAI NVASGAGSGL CGALFGSPFF LVKTRMQSYS PKFPVGQQYG YKHIFNAFSR
IIKENGVKGL FVGADAAILR TVSGSSVQLP IYNWAKRMIE HYNLLEEGMI KHLTASAVSG
FGVCCTMQIF DTVMTRMYNQ KNKELYKNPI DCILKTIRSE GFFALYKGFG AHLARIAPHT
IFCLTFVEQT NKLFLKFQKD
