ID   OADB1_SALTI             Reviewed;         433 AA.
AC   Q8Z9M6;
DT   15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=Oxaloacetate decarboxylase beta chain 1;
DE            EC=7.2.4.2;
GN   Name=oadB1; Synonyms=oadB; OrderedLocusNames=STY0063, t0056;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC       Na(+) translocation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC         pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC   -!- COFACTOR:
CC       Name=Na(+); Xref=ChEBI:CHEBI:29101;
CC   -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the GcdB/MmdB/OadB family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD01209.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO67789.1; -; Genomic_DNA.
DR   RefSeq; NP_454665.1; NC_003198.1.
DR   RefSeq; WP_000444842.1; NZ_QGFI01000074.1.
DR   AlphaFoldDB; Q8Z9M6; -.
DR   SMR; Q8Z9M6; -.
DR   STRING; 220341.16501338; -.
DR   EnsemblBacteria; AAO67789; AAO67789; t0056.
DR   KEGG; stt:t0056; -.
DR   KEGG; sty:STY0063; -.
DR   PATRIC; fig|220341.7.peg.63; -.
DR   eggNOG; COG1883; Bacteria.
DR   HOGENOM; CLU_036168_0_0_6; -.
DR   OMA; VGAMIDF; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005661; OadB_MmdB.
DR   PANTHER; PTHR35806; PTHR35806; 1.
DR   Pfam; PF03977; OAD_beta; 1.
DR   PIRSF; PIRSF015658; MmdB_OadB; 1.
DR   TIGRFAMs; TIGR01109; Na_pump_decarbB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Sodium; Sodium transport;
KW   Translocase; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..433
FT                   /note="Oxaloacetate decarboxylase beta chain 1"
FT                   /id="PRO_0000218565"
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        339..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        413..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   433 AA;  44939 MW;  8B06DC6019B84357 CRC64;
     MESLNALLQG MGLMHLGAGQ AIMLLVSLLL LWLAIAKKFE PLLLLPIGFG GLLSNIPEAG
     MALTALESLL AHHDAGQLAV IAAKLNCAPD VHAIKEALAL ALPSVQNQME NLAVDMGYTP
     GVLALFYKVA IGSGVAPLVI FMGVGAMTDF GPLLANPRTL LLGAAAQFGI FATVLGALTL
     NYFGLIAFTL PQAAAIGIIG GADGPTAIYL SGKLAPELLG AIAVAAYSYM ALVPLIQPPI
     MRALTSEKER KIRMVQLRTV SKREKILFPV VLLLLVALLL PDAAPLLGMF CFGNLMRESG
     VVERLSDTVQ NGLINIVTIF LGLSVGAKLV ADKFLQPQTL GILLLGVIAF GIGTAAGVLM
     AKLLNLCSKN KINPLIGSAG VSAVPMAARV SNKVGLESDA QNFLLMHAMG PNVAGVIGSA
     IAAGVMLKYV LAM