ID   OADB2_SALTY             Reviewed;         433 AA.
AC   Q03031;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Oxaloacetate decarboxylase beta chain 2;
DE            EC=7.2.4.2;
GN   Name=oadB2; Synonyms=oadB; OrderedLocusNames=STM3351;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=1331067; DOI=10.1016/s0021-9258(18)50017-x;
RA   Woehlke G., Wifling K., Dimroth P.;
RT   "Sequence of the sodium ion pump oxaloacetate decarboxylase from Salmonella
RT   typhimurium.";
RL   J. Biol. Chem. 267:22798-22803(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC       Na(+) translocation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC         pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC   -!- COFACTOR:
CC       Name=Na(+); Xref=ChEBI:CHEBI:29101;
CC   -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the GcdB/MmdB/OadB family. {ECO:0000305}.
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DR   EMBL; M96434; AAA02974.1; -; Unassigned_DNA.
DR   EMBL; AE006468; AAL22220.1; -; Genomic_DNA.
DR   PIR; C44465; C44465.
DR   RefSeq; NP_462261.1; NC_003197.2.
DR   RefSeq; WP_000444803.1; NC_003197.2.
DR   AlphaFoldDB; Q03031; -.
DR   SMR; Q03031; -.
DR   STRING; 99287.STM3351; -.
DR   TCDB; 3.B.1.1.1; the na(+)-transporting carboxylic acid decarboxylase (nat-dc) family.
DR   PaxDb; Q03031; -.
DR   EnsemblBacteria; AAL22220; AAL22220; STM3351.
DR   GeneID; 1254874; -.
DR   KEGG; stm:STM3351; -.
DR   PATRIC; fig|99287.12.peg.3552; -.
DR   HOGENOM; CLU_036168_0_0_6; -.
DR   PhylomeDB; Q03031; -.
DR   BioCyc; SENT99287:STM3351-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005661; OadB_MmdB.
DR   PANTHER; PTHR35806; PTHR35806; 1.
DR   Pfam; PF03977; OAD_beta; 1.
DR   PIRSF; PIRSF015658; MmdB_OadB; 1.
DR   TIGRFAMs; TIGR01109; Na_pump_decarbB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Reference proteome; Sodium;
KW   Sodium transport; Translocase; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..433
FT                   /note="Oxaloacetate decarboxylase beta chain 2"
FT                   /id="PRO_0000218566"
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        339..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        413..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   433 AA;  44923 MW;  1B29B1376B4632A1 CRC64;
     MESLNALLQG MGLMHLGAGQ AIMLLVSLLL LWLAIAKKFE PLLLLPIGFG GLLSNIPEAG
     LALTALESLL AHHDAGQLAV IAAKLHCAPD VHAIKEALAL ALPSVQNQME NLAVDMGYTP
     GVLALFYKVA IGSGVAPLVI FMGVGAMTDF GPLLANPRTL LLGAAAQFGI FATVLGALTL
     NYFGLISFTL PQAAAIGIIG GADGPTAIYL SGKLAPELLG AIAVAAYSYM ALVPLIQPPI
     MKALTSETER KIRMVQLRTV SKREKILFPV VLLMLVALLL PDAAPLLGMF CFGNLMRESG
     VVERLSDTVQ NGLINIVTIF LGLSVGAKLV ADKFLQPQTL GILLLGVIAF GIGTAAGVLM
     AKLLNLCSKN KINPLIGSAG VSAVPMAARV SNKVGLESDA QNFLLMHAMG PNVAGVIGSA
     IAAGVMLKYV LAM