ID   OADB_HAEDU              Reviewed;         435 AA.
AC   Q9RF98;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Oxaloacetate decarboxylase beta chain;
DE            EC=7.2.4.2;
GN   Name=oadB; OrderedLocusNames=HD_0782;
OS   Haemophilus ducreyi (strain 35000HP / ATCC 700724).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=233412;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=35000HP / ATCC 700724;
RA   Zaretzky F.R., Cole L.E., Kawula T.H.;
RT   "Identification of a putative oxaloacetate decarboxylase and cytochrome-c-
RT   peroxidase in Haemophilus ducreyi.";
RL   Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=35000HP / ATCC 700724;
RA   Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L.,
RA   Nguyen D., Wang J., Forst C., Hood L.;
RT   "The complete genome sequence of Haemophilus ducreyi.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC       Na(+) translocation. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC         pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC   -!- COFACTOR:
CC       Name=Na(+); Xref=ChEBI:CHEBI:29101; Evidence={ECO:0000250};
CC   -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GcdB/MmdB/OadB family. {ECO:0000305}.
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DR   EMBL; AF200362; AAF14627.1; -; Genomic_DNA.
DR   EMBL; AE017143; AAP95685.1; -; Genomic_DNA.
DR   RefSeq; WP_010944735.1; NC_002940.2.
DR   AlphaFoldDB; Q9RF98; -.
DR   SMR; Q9RF98; -.
DR   STRING; 233412.HD_0782; -.
DR   EnsemblBacteria; AAP95685; AAP95685; HD_0782.
DR   KEGG; hdu:HD_0782; -.
DR   eggNOG; COG1883; Bacteria.
DR   HOGENOM; CLU_036168_0_0_6; -.
DR   OMA; PMIADPK; -.
DR   Proteomes; UP000001022; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005661; OadB_MmdB.
DR   PANTHER; PTHR35806; PTHR35806; 1.
DR   Pfam; PF03977; OAD_beta; 1.
DR   PIRSF; PIRSF015658; MmdB_OadB; 1.
DR   TIGRFAMs; TIGR01109; Na_pump_decarbB; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Reference proteome; Sodium;
KW   Sodium transport; Translocase; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..435
FT                   /note="Oxaloacetate decarboxylase beta chain"
FT                   /id="PRO_0000218562"
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        215..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        267..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        309..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        340..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        404..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   435 AA;  45816 MW;  5DEBB54CB0DCC10B CRC64;
     MESIIALFQG MGIMHITLGQ VIMIIVSLIL LWLAIARRFE PLLLLPIGFG GLLSNIPEAG
     LAMTALDHLL HYAHTEQLTI IAEKVNSSSL DVHTIKQAIA FAPPSVQNEL EVIASDLGYN
     AGILALFYKV AIGYGVAPLI IFMGVGAMTD FGPLLANPRT LLLGAAAQFG IFTTVLGALG
     LNWLGIIDFS LPQAAAIGII GGADGPTAIY LASKLAPELL GAIAVAAYSY MALVPLIQPP
     IMKALTTEQE RKIRMVQLRT VSAREKIVFP IVLLLLVALL LPDAAPLLGM FCFGNLMRAS
     GVVERLNETA QNALINIVTI FLGLSVGAKL VADKFLQPQT LGILLLGIVA FAIGTASGVI
     MAKIMNAFSK HKINPLIGSA GVSAVPMAAR VSNKIGLEAD KQNFLLMHAM GPNVAGVISS
     AIAAGIMLKY ISTMI