ID   OADB_KLEPN              Reviewed;         433 AA.
AC   P13156;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2001, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Oxaloacetate decarboxylase beta chain;
DE            EC=7.2.4.2;
GN   Name=oadB;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RX   PubMed=2549031; DOI=10.1016/s0021-9258(18)63756-1;
RA   Laussermair E., Schwarz E., Oesterhelt D., Reinke H., Beyreuther K.,
RA   Dimroth P.;
RT   "The sodium ion translocating oxaloacetate decarboxylase of Klebsiella
RT   pneumoniae. Sequence of the integral membrane-bound subunits beta and
RT   gamma.";
RL   J. Biol. Chem. 264:14710-14715(1989).
CC   -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC       Na(+) translocation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC         pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC   -!- COFACTOR:
CC       Name=Na(+); Xref=ChEBI:CHEBI:29101;
CC   -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- PTM: The N-terminus is blocked.
CC   -!- SIMILARITY: Belongs to the GcdB/MmdB/OadB family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA25118.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M26290; AAA25118.1; ALT_INIT; Genomic_DNA.
DR   PIR; B36505; B36505.
DR   RefSeq; WP_074193734.1; NZ_FLDC01000033.1.
DR   AlphaFoldDB; P13156; -.
DR   SMR; P13156; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005661; OadB_MmdB.
DR   PANTHER; PTHR35806; PTHR35806; 1.
DR   Pfam; PF03977; OAD_beta; 1.
DR   PIRSF; PIRSF015658; MmdB_OadB; 1.
DR   TIGRFAMs; TIGR01109; Na_pump_decarbB; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Direct protein sequencing; Ion transport; Membrane; Sodium;
KW   Sodium transport; Translocase; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..433
FT                   /note="Oxaloacetate decarboxylase beta chain"
FT                   /id="PRO_0000218563"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        180..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        222..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        308..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        339..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        409..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   433 AA;  44878 MW;  50AB80365EE46421 CRC64;
     MESLNALIQG LGLMHLGAGQ AIMLLVSLLL LWLAIAKKFE PLLLLPIGFG GLLSNIPEAG
     LALTALESLL AHRDPAQLAV IAAKLHCAPD VHAIKAALAL ALPSVQGQME SLAVDMGYSA
     GVLAIFYKVA IGSGIAPLVI FMGVGAMTDF GPLLANPRTL LLGAAAQFGI FATVLGALTL
     NYFGIISFTL PQAAAIGIIG GADGPTAIYL SGKLAPELLG AIAVAAYSYM ALVPLIQPPI
     MKALTTDKER KIRMVQLRTV SKREKILFPA VLLLLVALLL PDAAPLLGMF CFGNLMRESG
     VVERLSDTVQ NALINIVTIF LGLSVGAKLV ADKFLQPQTL GILVLGVIAF CVGTAAGVLM
     AKLMNVFSRH KINPLIGSAG VSAVPMAARV SNKVGLEADG QNFLLMHAMG PNVAGVIGSA
     IAAGVMLKYV LAM