OADG1_SALTI
ID OADG1_SALTI Reviewed; 79 AA.
AC Q8Z9M5;
DT 15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 115.
DE RecName: Full=Oxaloacetate decarboxylase gamma chain 1;
DE EC=7.2.4.2;
GN Name=oadG1; OrderedLocusNames=STY0065, t0058;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC Na(+) translocation. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC -!- COFACTOR:
CC Name=Na(+); Xref=ChEBI:CHEBI:29101; Evidence={ECO:0000250};
CC -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OadG family. {ECO:0000305}.
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DR EMBL; AL513382; CAD01211.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO67791.1; -; Genomic_DNA.
DR RefSeq; NP_454667.1; NC_003198.1.
DR RefSeq; WP_001001151.1; NZ_WSUO01000005.1.
DR AlphaFoldDB; Q8Z9M5; -.
DR SMR; Q8Z9M5; -.
DR STRING; 220341.16501340; -.
DR EnsemblBacteria; AAO67791; AAO67791; t0058.
DR KEGG; stt:t0058; -.
DR KEGG; sty:STY0065; -.
DR PATRIC; fig|220341.7.peg.65; -.
DR eggNOG; COG3630; Bacteria.
DR HOGENOM; CLU_168750_3_2_6; -.
DR OMA; EGINLMF; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015081; F:sodium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR HAMAP; MF_00404; OadG; 1.
DR InterPro; IPR005899; Na_pump_deCOase.
DR InterPro; IPR023424; OadG.
DR Pfam; PF04277; OAD_gamma; 1.
DR TIGRFAMs; TIGR01195; oadG_fam; 1.
PE 3: Inferred from homology;
KW Cell membrane; Ion transport; Membrane; Sodium; Sodium transport;
KW Translocase; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..79
FT /note="Oxaloacetate decarboxylase gamma chain 1"
FT /id="PRO_0000216457"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 79 AA; 8623 MW; 27700EDEF783B450 CRC64;
MNEAVLLGEG FTLMFLGMGF VLSFLFLLIF AIRGMSAVIT RFFPEPVAAP APRAVPAVDD
FTRLKPVIAA AIHHHRLNA