ID   OADG2_SALTY             Reviewed;          84 AA.
AC   Q03032;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 2.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=Oxaloacetate decarboxylase gamma chain 2;
DE            EC=7.2.4.2;
GN   Name=oadG2; Synonyms=oadG; OrderedLocusNames=STM3353;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=1331067; DOI=10.1016/s0021-9258(18)50017-x;
RA   Woehlke G., Wifling K., Dimroth P.;
RT   "Sequence of the sodium ion pump oxaloacetate decarboxylase from Salmonella
RT   typhimurium.";
RL   J. Biol. Chem. 267:22798-22803(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC       Na(+) translocation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC         pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC   -!- COFACTOR:
CC       Name=Na(+); Xref=ChEBI:CHEBI:29101;
CC   -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the OadG family. {ECO:0000305}.
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DR   EMBL; M96434; AAA02972.1; -; Unassigned_DNA.
DR   EMBL; AE006468; AAL22222.1; -; Genomic_DNA.
DR   PIR; A44465; A44465.
DR   RefSeq; NP_462263.1; NC_003197.2.
DR   RefSeq; WP_000180114.1; NC_003197.2.
DR   PDB; 6IVA; X-ray; 4.40 A; B/D/F=1-84.
DR   PDB; 6IWW; EM; 3.90 A; B/D/F=1-84.
DR   PDBsum; 6IVA; -.
DR   PDBsum; 6IWW; -.
DR   AlphaFoldDB; Q03032; -.
DR   SMR; Q03032; -.
DR   STRING; 99287.STM3353; -.
DR   TCDB; 3.B.1.1.1; the na(+)-transporting carboxylic acid decarboxylase (nat-dc) family.
DR   PaxDb; Q03032; -.
DR   EnsemblBacteria; AAL22222; AAL22222; STM3353.
DR   GeneID; 1254876; -.
DR   KEGG; stm:STM3353; -.
DR   PATRIC; fig|99287.12.peg.3554; -.
DR   HOGENOM; CLU_168750_3_2_6; -.
DR   OMA; IATVIMS; -.
DR   PhylomeDB; Q03032; -.
DR   BioCyc; SENT99287:STM3353-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015081; F:sodium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR   HAMAP; MF_00404; OadG; 1.
DR   InterPro; IPR005899; Na_pump_deCOase.
DR   InterPro; IPR023424; OadG.
DR   Pfam; PF04277; OAD_gamma; 1.
DR   TIGRFAMs; TIGR01195; oadG_fam; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell membrane; Ion transport; Membrane; Reference proteome;
KW   Sodium; Sodium transport; Translocase; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..84
FT                   /note="Oxaloacetate decarboxylase gamma chain 2"
FT                   /id="PRO_0000216458"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        52..53
FT                   /note="KA -> N (in Ref. 1; AAA02972)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   84 AA;  8956 MW;  66D4C2527B4B63E8 CRC64;
     MTNAALLLGE GFTLMFLGMG FVLAFLFLLI FAIRGMSAAV NRFFPEPAPA PKAAPAAAAP
     VVDDFTRLKP VIAAAIHHHH RLNA