ID   ARRB_DROMI              Reviewed;         401 AA.
AC   P19108;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Phosrestin-1;
DE   AltName: Full=49 kDa arrestin-like protein;
DE   AltName: Full=Arrestin-2;
DE   AltName: Full=Arrestin-B;
DE   AltName: Full=Phosrestin I;
GN   Name=Arr2; Synonyms=ArrB;
OS   Drosophila miranda (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7229;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=S204;
RX   PubMed=2216789; DOI=10.1093/nar/18.19.5894;
RA   Krishnan R., Ganguly R.;
RT   "Nucleotide sequence of the arrestin-like 49 Kd protein gene of Drosophila
RT   miranda.";
RL   Nucleic Acids Res. 18:5894-5894(1990).
CC   -!- FUNCTION: Undergoes light-induced phosphorylation, probably plays an
CC       important role in the photoreceptor transduction.
CC   -!- TISSUE SPECIFICITY: Inner and outer segments, and the inner plexiform
CC       regions of the retina.
CC   -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR   EMBL; X54084; CAA38019.1; -; Genomic_DNA.
DR   PIR; S11566; S11566.
DR   AlphaFoldDB; P19108; -.
DR   SMR; P19108; -.
DR   FlyBase; FBgn0012552; Dmir\Arr2.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.640; -; 1.
DR   Gene3D; 2.60.40.840; -; 1.
DR   InterPro; IPR000698; Arrestin.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR017864; Arrestin_CS.
DR   InterPro; IPR014753; Arrestin_N.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR11792; PTHR11792; 1.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   Pfam; PF00339; Arrestin_N; 1.
DR   PRINTS; PR00309; ARRESTIN.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SUPFAM; SSF81296; SSF81296; 2.
DR   PROSITE; PS00295; ARRESTINS; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Sensory transduction; Vision.
FT   CHAIN           1..401
FT                   /note="Phosrestin-1"
FT                   /id="PRO_0000205218"
SQ   SEQUENCE   401 AA;  45014 MW;  E46EEBC2485AF99C CRC64;
     MVVSVKVFKK ATPNGKVTFY LGRRDFIDHL DYCDPVDGVI VVEPEYLKNR KVFGQLATTY
     RYGREEDEVM GVKFSKELIL SRDEIVPMTN PNMEMTPMQE KLVRKLGSNA HPFTFHFPPN
     SPSSVTLQQE GDDNGKPLGV EYTIRAFVGD SEDDRQHKRS MVSLVIKKLQ YAPLNRGQRL
     PSSLVSKGFT FSNGKISLEV TLDREIYYHG EKTAATVQVS NNSKKSVKSI KCFIVQHTEI
     TMVNAQFSKH VAQLETKEGC PITPGANLTK TFYLIPLAAN NKDRHGIALD GHLKDEDVNL
     ASSTMVQEGK NTGDACGIVI SYSVRIKLNC GTLGGEMQTD VPFKLLQPAP GTIEKKRSNA
     MKKMKSIEQH RNVKGYYQDD DDNIVFEDFA KMRMNNVNMA D