OADG_KLEP7
ID OADG_KLEP7 Reviewed; 83 AA.
AC A6T4H1;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Probable oxaloacetate decarboxylase gamma chain {ECO:0000255|HAMAP-Rule:MF_00404};
DE EC=7.2.4.2 {ECO:0000255|HAMAP-Rule:MF_00404};
GN Name=oadG {ECO:0000255|HAMAP-Rule:MF_00404};
GN OrderedLocusNames=KPN78578_00310; ORFNames=KPN_00032;
OS Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=272620;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700721 / MGH 78578;
RG The Klebsiella pneumonia Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC Na(+) translocation. {ECO:0000255|HAMAP-Rule:MF_00404}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00404};
CC -!- COFACTOR:
CC Name=Na(+); Xref=ChEBI:CHEBI:29101;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00404};
CC -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC {ECO:0000255|HAMAP-Rule:MF_00404}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00404};
CC Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00404}.
CC -!- SIMILARITY: Belongs to the OadG family. {ECO:0000255|HAMAP-
CC Rule:MF_00404}.
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DR EMBL; CP000647; ABR75492.1; -; Genomic_DNA.
DR RefSeq; WP_011977638.1; NC_009648.1.
DR AlphaFoldDB; A6T4H1; -.
DR SMR; A6T4H1; -.
DR STRING; 272620.KPN_00032; -.
DR EnsemblBacteria; ABR75492; ABR75492; KPN_00032.
DR KEGG; kpn:KPN_00032; -.
DR HOGENOM; CLU_168750_3_2_6; -.
DR OMA; SIKFMIL; -.
DR Proteomes; UP000000265; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015081; F:sodium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR HAMAP; MF_00404; OadG; 1.
DR InterPro; IPR005899; Na_pump_deCOase.
DR InterPro; IPR023424; OadG.
DR Pfam; PF04277; OAD_gamma; 1.
DR TIGRFAMs; TIGR01195; oadG_fam; 1.
PE 3: Inferred from homology;
KW Cell membrane; Ion transport; Membrane; Reference proteome; Sodium;
KW Sodium transport; Translocase; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..83
FT /note="Probable oxaloacetate decarboxylase gamma chain"
FT /id="PRO_1000049821"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00404"
SQ SEQUENCE 83 AA; 8957 MW; 217FE7813E1DE734 CRC64;
MTDNAILLGE GFTLMFLGMG FVLVFLLLLI FAIRGMSLAV NRLFSEPPAA PKPAPAAVAP
ADDFARLKPA IVAAIHHHRR LHP
