位置:首页 > 蛋白库 > OADG_KLEPN
OADG_KLEPN
ID   OADG_KLEPN              Reviewed;          83 AA.
AC   P13155;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Oxaloacetate decarboxylase gamma chain;
DE            EC=7.2.4.2;
GN   Name=oadG;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RX   PubMed=2549031; DOI=10.1016/s0021-9258(18)63756-1;
RA   Laussermair E., Schwarz E., Oesterhelt D., Reinke H., Beyreuther K.,
RA   Dimroth P.;
RT   "The sodium ion translocating oxaloacetate decarboxylase of Klebsiella
RT   pneumoniae. Sequence of the integral membrane-bound subunits beta and
RT   gamma.";
RL   J. Biol. Chem. 264:14710-14715(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13882 / NBRC 13541 / NCTC 8172;
RX   PubMed=1577734; DOI=10.1016/s0021-9258(19)50375-1;
RA   van der Rest M.E., Siewe R.M., Abee T., Schwarz E., Oesterhelt D.,
RA   Konings W.N.;
RT   "Nucleotide sequence and functional properties of a sodium-dependent
RT   citrate transport system from Klebsiella pneumoniae.";
RL   J. Biol. Chem. 267:8971-8976(1992).
CC   -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC       Na(+) translocation.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC         pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC   -!- COFACTOR:
CC       Name=Na(+); Xref=ChEBI:CHEBI:29101;
CC   -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the OadG family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M26289; AAA25117.1; -; Genomic_DNA.
DR   EMBL; M83146; AAA25061.1; -; Genomic_DNA.
DR   PIR; A36505; A36505.
DR   RefSeq; WP_004151376.1; NZ_WXZY01000006.1.
DR   AlphaFoldDB; P13155; -.
DR   SMR; P13155; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015081; F:sodium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR   HAMAP; MF_00404; OadG; 1.
DR   InterPro; IPR005899; Na_pump_deCOase.
DR   InterPro; IPR023424; OadG.
DR   Pfam; PF04277; OAD_gamma; 1.
DR   TIGRFAMs; TIGR01195; oadG_fam; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Direct protein sequencing; Ion transport; Membrane; Sodium;
KW   Sodium transport; Translocase; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..83
FT                   /note="Oxaloacetate decarboxylase gamma chain"
FT                   /id="PRO_0000216451"
FT   TRANSMEM        11..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   83 AA;  8909 MW;  493A5B564975591D CRC64;
     MTDNAVLLGE GFTLMCLGMG FVLVFLLLLI FAIRGMSLAV NRLFPEPPAA PKPAPAAVAP
     ADDFARLKPA IVAAIHHHRR LHP
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024