OADG_VIBPA
ID OADG_VIBPA Reviewed; 85 AA.
AC Q87LR6;
DT 25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Probable oxaloacetate decarboxylase gamma chain {ECO:0000255|HAMAP-Rule:MF_00404};
DE EC=7.2.4.2 {ECO:0000255|HAMAP-Rule:MF_00404};
GN Name=oadG {ECO:0000255|HAMAP-Rule:MF_00404}; OrderedLocusNames=VP2545;
OS Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=223926;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIMD 2210633;
RX PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT distinct from that of V. cholerae.";
RL Lancet 361:743-749(2003).
CC -!- FUNCTION: Catalyzes the decarboxylation of oxaloacetate coupled to
CC Na(+) translocation. {ECO:0000255|HAMAP-Rule:MF_00404}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) +
CC pyruvate; Xref=Rhea:RHEA:57724, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16526, ChEBI:CHEBI:29101; EC=7.2.4.2;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00404};
CC -!- COFACTOR:
CC Name=Na(+); Xref=ChEBI:CHEBI:29101;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00404};
CC -!- SUBUNIT: Heterotrimer of an alpha, a beta and a gamma subunit.
CC {ECO:0000255|HAMAP-Rule:MF_00404}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00404};
CC Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00404}.
CC -!- SIMILARITY: Belongs to the OadG family. {ECO:0000255|HAMAP-
CC Rule:MF_00404}.
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DR EMBL; BA000031; BAC60808.1; -; Genomic_DNA.
DR RefSeq; NP_798924.1; NC_004603.1.
DR RefSeq; WP_011106067.1; NC_004603.1.
DR AlphaFoldDB; Q87LR6; -.
DR SMR; Q87LR6; -.
DR STRING; 223926.28807543; -.
DR EnsemblBacteria; BAC60808; BAC60808; BAC60808.
DR GeneID; 1190060; -.
DR KEGG; vpa:VP2545; -.
DR PATRIC; fig|223926.6.peg.2442; -.
DR eggNOG; COG3630; Bacteria.
DR HOGENOM; CLU_168750_2_1_6; -.
DR OMA; YLVQLMS; -.
DR Proteomes; UP000002493; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015451; F:decarboxylation-driven active transmembrane transporter activity; IEA:UniProtKB-EC.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015081; F:sodium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR HAMAP; MF_00404; OadG; 1.
DR InterPro; IPR005899; Na_pump_deCOase.
DR InterPro; IPR023424; OadG.
DR Pfam; PF04277; OAD_gamma; 1.
DR TIGRFAMs; TIGR01195; oadG_fam; 1.
PE 3: Inferred from homology;
KW Cell membrane; Ion transport; Membrane; Reference proteome; Sodium;
KW Sodium transport; Translocase; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..85
FT /note="Probable oxaloacetate decarboxylase gamma chain"
FT /id="PRO_0000216463"
FT TRANSMEM 11..33
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00404"
SQ SEQUENCE 85 AA; 8969 MW; D49DEDA9D4E1E038 CRC64;
MTNIGSLLVD AATLMVTGMA VVFIFLTILV YLVRLLSKLV PEEVPEPIAA PKTNTRVQST
SSAVSPQVVA AISAAIHQHR ASIAK
