OAF_MOUSE
ID OAF_MOUSE Reviewed; 282 AA.
AC Q8QZR4; Q3UD27;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Out at first protein homolog;
DE Flags: Precursor;
GN Name=Oaf; Synonyms=D9Ucla1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Bone marrow, and Spinal ganglion;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Liver;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the OAF family. {ECO:0000305}.
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DR EMBL; AK051349; BAC34610.1; -; mRNA.
DR EMBL; AK150279; BAE29435.1; -; mRNA.
DR EMBL; BC025514; AAH25514.1; -; mRNA.
DR EMBL; BC026022; AAH26022.1; -; mRNA.
DR EMBL; BC028824; AAH28824.1; -; mRNA.
DR EMBL; BC034836; AAH34836.1; -; mRNA.
DR CCDS; CCDS23091.1; -.
DR RefSeq; NP_848759.1; NM_178644.3.
DR AlphaFoldDB; Q8QZR4; -.
DR STRING; 10090.ENSMUSP00000034512; -.
DR iPTMnet; Q8QZR4; -.
DR PhosphoSitePlus; Q8QZR4; -.
DR SwissPalm; Q8QZR4; -.
DR CPTAC; non-CPTAC-3598; -.
DR MaxQB; Q8QZR4; -.
DR PaxDb; Q8QZR4; -.
DR PeptideAtlas; Q8QZR4; -.
DR PRIDE; Q8QZR4; -.
DR ProteomicsDB; 287877; -.
DR Antibodypedia; 49399; 83 antibodies from 21 providers.
DR Ensembl; ENSMUST00000034512; ENSMUSP00000034512; ENSMUSG00000032014.
DR GeneID; 102644; -.
DR KEGG; mmu:102644; -.
DR UCSC; uc009pbf.1; mouse.
DR CTD; 220323; -.
DR MGI; MGI:94852; Oaf.
DR VEuPathDB; HostDB:ENSMUSG00000032014; -.
DR eggNOG; ENOG502QWDA; Eukaryota.
DR GeneTree; ENSGT00390000012008; -.
DR HOGENOM; CLU_043995_1_0_1; -.
DR InParanoid; Q8QZR4; -.
DR OMA; CFITRLH; -.
DR OrthoDB; 1311469at2759; -.
DR PhylomeDB; Q8QZR4; -.
DR TreeFam; TF323953; -.
DR BioGRID-ORCS; 102644; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Oaf; mouse.
DR PRO; PR:Q8QZR4; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q8QZR4; protein.
DR Bgee; ENSMUSG00000032014; Expressed in left lobe of liver and 183 other tissues.
DR ExpressionAtlas; Q8QZR4; baseline and differential.
DR Genevisible; Q8QZR4; MM.
DR InterPro; IPR026315; Oaf.
DR PANTHER; PTHR13423; PTHR13423; 1.
DR Pfam; PF14941; OAF; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..282
FT /note="Out at first protein homolog"
FT /id="PRO_0000292428"
FT CONFLICT 140
FT /note="V -> A (in Ref. 1; BAE29435)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 282 AA; 31524 MW; 3F467B20B7C01B9B CRC64;
MRPPGCRDVP SARPALPLLL LLLSPLLLGA LHGVGAGSGA PAELRVRVRL PDSQVIEESL
QADSDADSIS LDLRKPDGTL ISFIADFKKD VKIFRALILG ELEKGQSQFQ ALCFVTRLHH
NDIIPSEAMA KLRQKNPRAV RQAEEVRGLE QLHMDIAVNF SQGGLLSPHL HNVCAEATDA
IYTRQEDVQF WTERGVDSSV FEALPKALEQ AELPRCGRVG DRGKPCTCHY SLSLAWYPCM
LKYCHSRDRP APYKCGIRSC RKSYTFDFYV PQKQLCLWDE DP
