ID   ARRC_LITCT              Reviewed;         389 AA.
AC   P51481;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Arrestin-C;
DE   AltName: Full=Cone arrestin;
GN   Name=arr3;
OS   Lithobates catesbeianus (American bullfrog) (Rana catesbeiana).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Lithobates.
OX   NCBI_TaxID=8400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Retina;
RX   PubMed=8536686; DOI=10.1111/j.1432-1033.1995.437_b.x;
RA   Abdulaeva G., Hargrave P.A., Smith W.C.;
RT   "The sequence of arrestins from rod and cone photoreceptors in the frogs
RT   Rana catesbeiana and Rana pipiens. Localization of gene transcripts by
RT   reverse-transcription polymerase chain reaction on isolated
RT   photoreceptors.";
RL   Eur. J. Biochem. 234:437-442(1995).
CC   -!- FUNCTION: May play a role in an as yet undefined retina-specific signal
CC       transduction. Could bind to photoactivated-phosphorylated red/green
CC       opsins.
CC   -!- TISSUE SPECIFICITY: Retina and pineal gland.
CC   -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR   EMBL; U30268; AAC59749.1; -; mRNA.
DR   EMBL; X92401; CAA63138.1; -; mRNA.
DR   PIR; S68175; S68175.
DR   AlphaFoldDB; P51481; -.
DR   SMR; P51481; -.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.640; -; 1.
DR   Gene3D; 2.60.40.840; -; 1.
DR   InterPro; IPR033042; ARR3.
DR   InterPro; IPR000698; Arrestin.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR017864; Arrestin_CS.
DR   InterPro; IPR014753; Arrestin_N.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR11792; PTHR11792; 1.
DR   PANTHER; PTHR11792:SF19; PTHR11792:SF19; 1.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   Pfam; PF00339; Arrestin_N; 1.
DR   PRINTS; PR00309; ARRESTIN.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SUPFAM; SSF81296; SSF81296; 2.
DR   PROSITE; PS00295; ARRESTINS; 1.
PE   2: Evidence at transcript level;
KW   Sensory transduction; Vision.
FT   CHAIN           1..389
FT                   /note="Arrestin-C"
FT                   /id="PRO_0000205206"
SQ   SEQUENCE   389 AA;  43182 MW;  28D516EF51F387E0 CRC64;
     MADGSKVFKK TSPDGKITVY LAKRDYVDHV EFVEPVDGMI VIDPEYQKEK KVFVMMTCAF
     RYGRDDMELI GLSFRKDIYV QSCQVHPPLP GEKKALTPLQ EKLKAKLGGN SFPFSFNMAT
     NLPCSVTLQP GPEDSGKACG VDFEVKGFWG DDVEEKNSKK NVARLIIRKV QYAPETSGAA
     PHAEITKQFM MSDKPLQLEA SLNKEIHYHG EPIIVNVKIN NSTNKIVKKI KITVEQITDV
     VLYSLDKYTK VVCCEEMNDT VAANSAFTKA YQVTPLLANN REKRGLALDG KLKHGDTNLA
     SSTTLRPGMD KEVMGILVSY KIRVNLMASR GGILGDLISS DVSVELPLIL MHPKPAEGTT
     SAEDVVIEEF ARQKLQGEQD DEEDKEEAS