ID   ARRC_LITPI              Reviewed;         389 AA.
AC   P51482;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Arrestin-C;
DE   AltName: Full=Cone arrestin;
GN   Name=arr3;
OS   Lithobates pipiens (Northern leopard frog) (Rana pipiens).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Lithobates.
OX   NCBI_TaxID=8404;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Retina;
RX   PubMed=8536686; DOI=10.1111/j.1432-1033.1995.437_b.x;
RA   Abdulaeva G., Hargrave P.A., Smith W.C.;
RT   "The sequence of arrestins from rod and cone photoreceptors in the frogs
RT   Rana catesbeiana and Rana pipiens. Localization of gene transcripts by
RT   reverse-transcription polymerase chain reaction on isolated
RT   photoreceptors.";
RL   Eur. J. Biochem. 234:437-442(1995).
CC   -!- FUNCTION: May play a role in an as yet undefined retina-specific signal
CC       transduction. Could bind to photoactivated-phosphorylated red/green
CC       opsins.
CC   -!- TISSUE SPECIFICITY: Retina and pineal gland.
CC   -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR   EMBL; U30270; AAC59751.1; -; mRNA.
DR   EMBL; X92400; CAA63137.1; -; mRNA.
DR   PIR; S68172; S68172.
DR   AlphaFoldDB; P51482; -.
DR   SMR; P51482; -.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.640; -; 1.
DR   Gene3D; 2.60.40.840; -; 1.
DR   InterPro; IPR033042; ARR3.
DR   InterPro; IPR000698; Arrestin.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   InterPro; IPR011022; Arrestin_C-like.
DR   InterPro; IPR017864; Arrestin_CS.
DR   InterPro; IPR014753; Arrestin_N.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR11792; PTHR11792; 1.
DR   PANTHER; PTHR11792:SF19; PTHR11792:SF19; 1.
DR   Pfam; PF02752; Arrestin_C; 1.
DR   Pfam; PF00339; Arrestin_N; 1.
DR   PRINTS; PR00309; ARRESTIN.
DR   SMART; SM01017; Arrestin_C; 1.
DR   SUPFAM; SSF81296; SSF81296; 2.
DR   PROSITE; PS00295; ARRESTINS; 1.
PE   2: Evidence at transcript level;
KW   Sensory transduction; Vision.
FT   CHAIN           1..389
FT                   /note="Arrestin-C"
FT                   /id="PRO_0000205207"
SQ   SEQUENCE   389 AA;  43049 MW;  39C95360344D9BDD CRC64;
     MADGSKVFKK TSPDGKITVY LAKRDYVDHV EFVEPVDGMI VIDPEYQKEK KVFVTMTCAF
     RYGRDDMELI GLSFRKDIYV QSCQVHPPLP GEKKALTPLQ EKLKAKLGAN AFPFSFNMAT
     NLPCSVTLQP GPEDSGKACG VDFEVKGFWG DDVEEKVSKK NVARLIIRKV QYAPETAGAA
     PHAEITKQFM MSDKPLQLEA SLNKEIHYHG EPIIVNVKIN NSTNKIVKKI KITVEQITDV
     VLYSLDKYTK VVCCEEMNDT VAANSAFTKA YQVTPLLANN TEKRGLALDG KLKHGDTNLA
     SSTTLRPGMD KEVMGILVSY KIRVNLMASR GGILGDLISS DVSVELPLIL MHPKPAEGTT
     SAEDVVIEEF ARQKLQGEQD DDEDKEEAS