ID   ARSA_PROVB              Reviewed;         405 AA.
AC   Q46465;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Putative arsenical pump-driving ATPase;
DE            EC=7.3.2.7;
DE   AltName: Full=Arsenical resistance ATPase;
DE   AltName: Full=Arsenite-translocating ATPase;
DE   AltName: Full=Arsenite-transporting ATPase;
OS   Prosthecochloris vibrioformis (Chlorobium vibrioforme).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Prosthecochloris.
OX   NCBI_TaxID=1098;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=8327D;
RA   Chung S., Frank G., Zuber H., Bryant D.A.;
RT   "Genes encoding two chlorosome components from the green sulfur bacteria
RT   Chlorobium vibrioforme strain 8327D and Chlorobium tepidum.";
RL   Photosyn. Res. 41:261-275(1994).
CC   -!- FUNCTION: Anion-transporting ATPase. Catalyzes the extrusion of
CC       arsenite (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=arsenite(in) + ATP + H2O = ADP + arsenite(out) + H(+) +
CC         phosphate; Xref=Rhea:RHEA:11348, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29242, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.7;
CC   -!- SIMILARITY: Belongs to the arsA ATPase family. {ECO:0000305}.
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DR   EMBL; U09867; AAA18794.1; -; Unassigned_DNA.
DR   AlphaFoldDB; Q46465; -.
DR   SMR; Q46465; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0015446; F:ATPase-coupled arsenite transmembrane transporter activity; IEA:UniProtKB-EC.
DR   Gene3D; 2.60.40.790; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR025723; Anion-transp_ATPase-like_dom.
DR   InterPro; IPR040612; ArsA_HSP20-like.
DR   InterPro; IPR016300; ATPase_ArsA/GET3.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10803; PTHR10803; 1.
DR   Pfam; PF02374; ArsA_ATPase; 1.
DR   Pfam; PF17886; ArsA_HSP20; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00345; GET3_arsA_TRC40; 1.
PE   3: Inferred from homology;
KW   Arsenical resistance; ATP-binding; Nucleotide-binding; Translocase.
FT   CHAIN           1..405
FT                   /note="Putative arsenical pump-driving ATPase"
FT                   /id="PRO_0000152263"
FT   BINDING         8..15
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   405 AA;  45935 MW;  DE309391972EBC19 CRC64;
     MRILTFTGKG GVGKTSVSAA TAVRLSEMGH RTLVLSTDPA HSLSDSFNLQ LGAEPTKIKE
     NLHAIEVNPY VDLKENWHSV QKYYTRVFMA QGVSGVMADE MTILPGMEEL FSLLRIKRYK
     STGLYDALVL DTAPTGETLR LLSLPDTLSW GMKAVKNVNK YIVRPLSKPL SKMSDKIAYY
     IPPEDAIESV DQVFDELEDI RDILTDNVKS TVRLVMNAEK MSIKETMRAL TYLNLYGFKV
     DMVLVNKLLD AQENSGYLEK WKGIQQKYLG EIEEGFSPLP VKKLKMYDQE IVGVKSLEVF
     AHDIYGDTDP SDMMYDEPPI KFVRKGDIYE VQLKLMFANP VDIDVWVTGD ELFVQIGNQR
     KIITLPVSLT GLEPGDAVFR DKWLHIPFDL EKQGQHHRTR EFNKA