ID   OBP71_ANOGA             Reviewed;         228 AA.
AC   Q5TYJ0;
DT   01-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2014, sequence version 4.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=General odorant-binding protein 71;
DE   Flags: Precursor;
GN   Name=Obp71; ORFNames=AGAP012867;
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST;
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA   Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA   Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA   Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA   Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA   Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA   Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA   Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA   Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA   Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA   McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA   O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA   Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA   Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA   Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA   Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA   Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA   Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA   Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=23292137; DOI=10.1093/gbe/evs131;
RA   Manoharan M., Ng Fuk Chong M., Vaitinadapoule A., Frumence E.,
RA   Sowdhamini R., Offmann B.;
RT   "Comparative genomics of odorant binding proteins in Anopheles gambiae,
RT   Aedes aegypti, and Culex quinquefasciatus.";
RL   Genome Biol. Evol. 5:163-180(2013).
CC   -!- FUNCTION: Present in the aqueous fluid surrounding olfactory sensory
CC       dendrites and are thought to aid in the capture and transport of
CC       hydrophobic odorants into and through this fluid. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PBP/GOBP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAL42442.3; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AAAB01000326; EAL42442.3; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_561559.5; XM_561559.5.
DR   AlphaFoldDB; Q5TYJ0; -.
DR   SMR; Q5TYJ0; -.
DR   STRING; 7165.AGAP012867-PA; -.
DR   PRIDE; Q5TYJ0; -.
DR   GeneID; 3292662; -.
DR   KEGG; aga:AgaP_AGAP012867; -.
DR   VEuPathDB; VectorBase:AGAP012867; -.
DR   eggNOG; ENOG502SBM2; Eukaryota.
DR   HOGENOM; CLU_119225_0_0_1; -.
DR   OrthoDB; 1290803at2759; -.
DR   Proteomes; UP000007062; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005549; F:odorant binding; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.238.20; -; 1.
DR   InterPro; IPR006170; PBP/GOBP.
DR   InterPro; IPR036728; PBP_GOBP_sf.
DR   Pfam; PF01395; PBP_GOBP; 1.
DR   SUPFAM; SSF47565; SSF47565; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Olfaction; Reference proteome; Secreted;
KW   Sensory transduction; Signal; Transport.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..228
FT                   /note="General odorant-binding protein 71"
FT                   /id="PRO_0000430411"
FT   REGION          50..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..70
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..101
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        111..131
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        138..199
FT                   /evidence="ECO:0000250"
FT   DISULFID        185..208
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   228 AA;  25432 MW;  2772DE28DC214CE9 CRC64;
     MCGAIVLLLL VGTSPAPVEG LRCRTGEGPS ADDVKRIVRT CMNKITNAGT MGEWGQRDRN
     GEEQQMMRDY GRSHRRRKRQ YYGGQTSGSS SSGSAGEHSY NGRASPQYGE AGQGGNGTRS
     GGNSSSSSSS TIERDRACLM QCFFEEMKAT NADGFPEKHK VLHVITKDIR EHELREFYVD
     SIQECFHMLG LDNRLKDKCD YSMRFVTCLS DRFETNCDDW ESVTSAMF