OBP72_ANOGA
ID OBP72_ANOGA Reviewed; 121 AA.
AC A7UR17;
DT 01-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 61.
DE RecName: Full=General odorant-binding protein 72;
DE Flags: Fragment;
GN Name=Obp72; ORFNames=AGAP012714;
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST;
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2]
RP IDENTIFICATION.
RX PubMed=23292137; DOI=10.1093/gbe/evs131;
RA Manoharan M., Ng Fuk Chong M., Vaitinadapoule A., Frumence E.,
RA Sowdhamini R., Offmann B.;
RT "Comparative genomics of odorant binding proteins in Anopheles gambiae,
RT Aedes aegypti, and Culex quinquefasciatus.";
RL Genome Biol. Evol. 5:163-180(2013).
CC -!- FUNCTION: Present in the aqueous fluid surrounding olfactory sensory
CC dendrites and are thought to aid in the capture and transport of
CC hydrophobic odorants into and through this fluid. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PBP/GOBP family. {ECO:0000305}.
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DR EMBL; AAAB01008582; EDO64833.1; -; Genomic_DNA.
DR RefSeq; XP_001687816.1; XM_001687764.1.
DR AlphaFoldDB; A7UR17; -.
DR SMR; A7UR17; -.
DR STRING; 7165.AGAP012714-PA; -.
DR GeneID; 5668372; -.
DR KEGG; aga:AgaP_AGAP012714; -.
DR VEuPathDB; VectorBase:AGAP012714; -.
DR eggNOG; ENOG502SA47; Eukaryota.
DR HOGENOM; CLU_107288_0_0_1; -.
DR OMA; CTAEADP; -.
DR OrthoDB; 1461377at2759; -.
DR PhylomeDB; A7UR17; -.
DR Proteomes; UP000007062; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0035275; F:dibutyl phthalate binding; IBA:GO_Central.
DR GO; GO:0005549; F:odorant binding; IEA:InterPro.
DR GO; GO:0042048; P:olfactory behavior; IBA:GO_Central.
DR GO; GO:0007608; P:sensory perception of smell; IBA:GO_Central.
DR Gene3D; 1.10.238.20; -; 1.
DR InterPro; IPR006170; PBP/GOBP.
DR InterPro; IPR036728; PBP_GOBP_sf.
DR Pfam; PF01395; PBP_GOBP; 1.
DR SMART; SM00708; PhBP; 1.
DR SUPFAM; SSF47565; SSF47565; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Olfaction; Reference proteome; Secreted;
KW Sensory transduction; Transport.
FT CHAIN <1..121
FT /note="General odorant-binding protein 72"
FT /id="PRO_0000430412"
FT DISULFID 45..101
FT /evidence="ECO:0000250"
FT DISULFID 90..110
FT /evidence="ECO:0000250"
FT NON_TER 1
SQ SEQUENCE 121 AA; 13656 MW; D7B311F1D583FAD7 CRC64;
SITQEQLEKT ARTFRQVCQP KHKISDEVAD AVNRGVFADT KDFKCYVSCL LDIMQVARKG
KVNYEKSLKQ IDTMLPDHMK PAFRAGLEAC KSAAQGVKDH CEAAAILLQC FYKNNPKFVF
P