ID   OBPAL_CANAL             Reviewed;         429 AA.
AC   Q9UW21; Q59YW8; Q59YW9;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Oxysterol-binding protein-like protein OBPalpha;
GN   Name=OBPALPHA;
GN   OrderedLocusNames=C5_01775C_B {ECO:0000312|CGD:CAL0000202034};
GN   ORFNames=CaO19.10709/10710;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=10455055; DOI=10.1126/science.285.5431.1271;
RA   Hull C.M., Johnson A.D.;
RT   "Identification of a mating type-like locus in the asexual pathogenic yeast
RT   Candida albicans.";
RL   Science 285:1271-1275(1999).
CC   -!- MISCELLANEOUS: The C.albicans mating-type-like (MTL) locus contains, in
CC       addition to the genes for the regulatory proteins (MTLA1, MTLA2,
CC       MTLALPHA1 and MTLALPHA2), a and alpha idiomorphs of a
CC       phosphatidylinositol kinase (PIKA and PIKALPHA), a poly(A) polymerase
CC       (PAPA and PAPALPHA) and an oxysterol binding protein-like protein (OBPA
CC       and OBPALPHA). OBPALPHA is not represented in the genomic sequence of
CC       strain SC5314 because that haploid assembly includes the mating type a
CC       allele of this locus. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the OSBP family. {ECO:0000305}.
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DR   EMBL; AF167163; AAD51409.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9UW21; -.
DR   SMR; Q9UW21; -.
DR   PRIDE; Q9UW21; -.
DR   CGD; CAL0000202034; OBPALPHA.
DR   eggNOG; KOG2210; Eukaryota.
DR   HOGENOM; CLU_1927311_0_0_1; -.
DR   InParanoid; Q9UW21; -.
DR   OMA; DVHTHKK; -.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0044011; P:single-species biofilm formation on inanimate substrate; IMP:CGD.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   InterPro; IPR018494; Oxysterol-bd_CS.
DR   PANTHER; PTHR10972; PTHR10972; 1.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   SUPFAM; SSF144000; SSF144000; 1.
DR   PROSITE; PS01013; OSBP; 1.
PE   3: Inferred from homology;
KW   Lipid transport; Lipid-binding; Transport.
FT   CHAIN           1..429
FT                   /note="Oxysterol-binding protein-like protein OBPalpha"
FT                   /id="PRO_0000100384"
SQ   SEQUENCE   429 AA;  49741 MW;  259C73A904D5795D CRC64;
     MGLTAKLDKL KLKTTSEDIE DDSGHAKPDN SDDIDEVDSE YQNILLSIIA QLRPGMDLSK
     ITLPTFILEK KSMLERITNF FQIPKLLIDS NSIEDPLDRF IGVLRWYLAS WHISPKAVKK
     PLNPVLGEVF TCYWDELPNN KSAYYLSEQI SHHPPKSSYF YIMPEEKIRV DGVVIPKSRF
     LGNSSAAIME GCGYVTLGKW DNEVYVMNQP NVYVRGILFG KMRTELGDHM YVKCERNGLE
     ANIEFKTKGF IYGTYDAIEG IIKDSETQKE LFQISGKWNE VMYIKNIKTG KKEVLYDTRG
     SKTLKPKVRP LEEQWDFESR KLWKPTIAGL AKRNHELATE EKSKVENEQR IKAKKRLEDG
     VEFHPKFFRE VNENDNGVKN LEYVIYKKFD LKEDPEVLRE RLFTVAPIVP GQKFDEKFHY
     PAFKKPESN