ID   OCA5_ASHGO              Reviewed;         560 AA.
AC   Q753Y0;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 2.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; OrderedLocusNames=AFR192W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
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DR   EMBL; AE016819; AAS53563.2; -; Genomic_DNA.
DR   RefSeq; NP_985739.2; NM_211093.2.
DR   AlphaFoldDB; Q753Y0; -.
DR   STRING; 33169.AAS53563; -.
DR   PRIDE; Q753Y0; -.
DR   EnsemblFungi; AAS53563; AAS53563; AGOS_AFR192W.
DR   GeneID; 4621997; -.
DR   KEGG; ago:AGOS_AFR192W; -.
DR   eggNOG; ENOG502QVXN; Eukaryota.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   InParanoid; Q753Y0; -.
DR   OMA; LGPDIFW; -.
DR   Proteomes; UP000000591; Chromosome VI.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..560
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408205"
FT   DOMAIN          39..348
FT                   /note="Rab-GAP TBC"
FT   REGION          401..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          497..519
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..427
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   560 AA;  65472 MW;  1A9D52F67F3CAFBD CRC64;
     MALQRNSKQN QQQWYRELVN KVIQLLQQND HDSLALIARN CGVPPQLRHL VWPVLLKYHP
     FVISPSILSN TLIFDKTEDK WVYECENRAR RDVEQAVMHD LQKFFVNKRS DQHMPLPDIE
     QHMRFLRDTI MRFLDKWERV FKYEVALAWI AIGLAEWVPI DGWGESAPGG GGVCSEDMAL
     PKGRSTDVPV LQGKRHHITI RSLYKEYPLP RELSSRLTKR CFNFYDTFER LVLVILHCPD
     VTRTKMKVAN GRNYPFISGG DVLFQTQLFF KIFQMTLPEL YQPFTDEESL QSSRKADWIY
     WWFKACGAKV MHKQDRAHLW DVLLGWRPHP STLNFYLDYN NKSFAHLYNT KLNLDPQFFH
     KVCKHGNDHF WFPDLDTLPL GSPGLETDCQ VVNELIRHNS YESKDTGAPG TPSKTSQAGN
     NYRSPIRPSQ KHQKDIPFSL IDPHVQLIFI YIAILQQNEF KLLEFEEAEI TEFLTKVPLL
     SKTDDYSYKR LYDEESTSLS STDTEDSQNS SSRPSTSSHM MIEVGNDDKI ANTFDDLSQL
     AGDIWRKWMW FEFEESQDSV