ID   OCA5_CANAL              Reviewed;         716 AA.
AC   Q5ADS3; A0A1D8PKP9;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; OrderedLocusNames=CAALFM_C307290WA;
GN   ORFNames=CaO19.14061, CaO19.6769;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
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DR   EMBL; CP017625; AOW28731.1; -; Genomic_DNA.
DR   RefSeq; XP_719865.1; XM_714772.1.
DR   AlphaFoldDB; Q5ADS3; -.
DR   SMR; Q5ADS3; -.
DR   STRING; 237561.Q5ADS3; -.
DR   PRIDE; Q5ADS3; -.
DR   GeneID; 3638430; -.
DR   KEGG; cal:CAALFM_C307290WA; -.
DR   CGD; CAL0000188408; orf19.14061.
DR   VEuPathDB; FungiDB:C3_07290W_A; -.
DR   eggNOG; ENOG502QVXN; Eukaryota.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   InParanoid; Q5ADS3; -.
DR   OMA; LGPDIFW; -.
DR   OrthoDB; 467078at2759; -.
DR   PRO; PR:Q5ADS3; -.
DR   Proteomes; UP000000559; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..716
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408206"
FT   DOMAIN          100..459
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          132..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          352..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          502..521
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          554..582
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          634..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..205
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        354..376
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        504..518
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        634..663
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   716 AA;  81933 MW;  88C5A3E9DA12D13C CRC64;
     MLQTSKGSNS SSTSSSRSAS ISTATPNTIV EDEELLCDPK SELTPPAVAN PLRPVSKSNT
     SVEDDSKPSF TYDLDVFNLC KEYLNTRNHH GLALIARQKG IPPILRFKVW PILLKSHPFV
     ISPFIQPDSE LLNESTSSRS NSSSSSTGSN TPLSTAPGSI KDAAIIDGDA NDNDNDSNSN
     SNDDDNDRDD NDANTKEKEE DERNNKIREK IKRDLAKYIQ RLKYSQSKYT VSETEHEILS
     ILENAIMKFT LKWGKIIKYD SSLTWIALNL AEWFPPIPKT PWVLVGKEYS SSHQSLIVNF
     LDDYSNYIDN IPDLREYLER LIYHDEKIST ISFREVYERL VLVLLHCPQP VSRRKKSDNQ
     GSNQRRNQSE VQKDQQSFKV NKTTLPKTGG TIEERVSYFI YCLRKLIPEL SQYFHEEQIL
     TKFGCLDDEW LIWWLKFCGT KVWSKYDRGR IWDFMLGWRL KNPKRDFNYY YEKLNYVNRN
     TLEKLGPDIF WSVGNEEEDI SGDNNVDANA NEINNTEKTE TGKLVKREGD IKRSSFKDLV
     NELSNELHIS KRVSTDEVAT STSSPATTKM ASSSSTSSTL TPNVSIPFSR VDPHVALIFI
     SLSLLKSKEN ILVELDQHEI RQFLSRLPSK SYKYNQKRST RQKRTSYASN ASSTSNSPMG
     QSPVDRDEDS IFPTSRIVIS NDSKDQKHKV NFIDNIISEA GELWRKWLWS EMVEDN