ID   OCA5_CANAW              Reviewed;         717 AA.
AC   C4YP90;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; ORFNames=CAWG_03037;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
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DR   EMBL; CM000310; EEQ44749.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4YP90; -.
DR   STRING; 5476.C4YP90; -.
DR   EnsemblFungi; EEQ44749; EEQ44749; CAWG_03037.
DR   VEuPathDB; FungiDB:CAWG_03037; -.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   OMA; LGPDIFW; -.
DR   Proteomes; UP000001429; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..717
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408207"
FT   DOMAIN          100..460
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          132..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          353..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          503..522
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          555..583
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          636..670
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..158
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..209
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        355..377
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        505..519
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        636..664
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   717 AA;  81986 MW;  51896A764DD992BC CRC64;
     MLQTSKGSNS SSTSSSRSAS ISTATPNTIV EDEELLCGPK SELTPPAVAN PLRPVSKSNT
     SVEDDSKPSF TYDLDVFNLC KEYLNTRNHH GLALIARQKG IPPILRFKVW PILLKSHPFV
     ISPFIQPDSE LLNESTSSRS NSSSSSSTGS NTPLSTAPGS IKDAAIIDGD ANDNDNDSNS
     NSNDDDNDRD NNDANTKEKE EDEQNNKIRE KIKRDLAKYI QRLKYSQSKY TVSETEHEIL
     SILENAIMKF TLKWGKIIKY DSSLTWIALN LAEWFPPIPK TPWVLVGKEY SSSHQSLIVN
     FLDDYSNYID NIPDLREYLE RLIYHDEKIS TISFREVYER LVLVLLHCPQ PVSRRKKSDN
     QGQNQRRNQS EVQKDQQSFK VNKTTLPKTG GTIEERVSYF IYCLRKLIPE LSQYFHEEQI
     LTKFGCLDDE WLIWWLKFCG TKVWSKYDRG RIWDFMLGWR LKNPKRDFNY YYEKLNYVNR
     NTLEKLGPDI FWSVGNEEED ISGDNNVDAN ANEINNTEKT ETGKLVKREG DIKRSSFKDL
     VNELSNELHI SKRVSTDEVA TSTSSPATTK MASSSSTSST LTPNVSIPFS RVDPHVALIF
     ISLSLLKSKE NILVELDQHE IRQFLSRLPS KSYKYNQKRS TRQKRISYAS NASSTSNSPM
     GQSPVDRDED SIFPTSRIVI SNDSKDQKHK VNFIDNIISE AGELWRKWLW SEMVEDN