ID   OCA5_CANTT              Reviewed;         663 AA.
AC   C5MHS7;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 40.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; ORFNames=CTRG_05620;
OS   Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-3404 / T1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
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DR   EMBL; GG692403; EER30624.1; -; Genomic_DNA.
DR   RefSeq; XP_002551322.1; XM_002551276.1.
DR   AlphaFoldDB; C5MHS7; -.
DR   STRING; 5482.XP_002551322.1; -.
DR   PRIDE; C5MHS7; -.
DR   EnsemblFungi; EER30624; EER30624; CTRG_05620.
DR   GeneID; 8300833; -.
DR   KEGG; ctp:CTRG_05620; -.
DR   VEuPathDB; FungiDB:CTRG_05620; -.
DR   eggNOG; ENOG502QVXN; Eukaryota.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   OrthoDB; 467078at2759; -.
DR   Proteomes; UP000002037; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   SUPFAM; SSF47923; SSF47923; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..663
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408210"
FT   DOMAIN          95..427
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..178
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          575..611
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..168
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   663 AA;  76384 MW;  93E2ACD760A7484A CRC64;
     MFENSAKESS MSSSRSSGSP DVSALVTPNN IEEVKEPELL KIIPPQGPPP SSSGSISLED
     FKPSFNYDLE VFNLCKEYLN TRNHHGLALI TRQKGIPPFL RFKVWPILLK SHPFVINPFI
     QPDQDLMKES SSSSTSSSTS TTGSPINSEH SSIKDGILNQ GNDTREEPQP QPSDPHEEIR
     QKIKRDLGKY IQRLKYSQSK YTVSELEHQI LSILEDSVLK FILKWGKIIK YDSSLTWVAL
     NLAEWFPPIP KTPWVLVGRD YSTADSSLVI NLMDDYSNYI DNIPDLKSYL ENLIYNDEKI
     SNMSFREVFE RLVLVLLHCP EPESRRKKSE VSKHASDLDH SHVQSMKVNK TTLPKTGGTI
     EERVSYFIYC LRKLLPELSQ YFHEEQILTK FGCLDDEWLI WWLKFCGTKV WSKYDRGRIW
     DFMLGWRLKN PRRDFNYYYE KLNYVNRNTL EKLGPDIFWS VGSEDNNNVE RFKNNQGLTR
     DKKTSSFKDL INDLHNDLHI SKKVSTSPGV RNTSHSSILD SSPNFSIPFS RVDPHIALIF
     ISLSLLKSKE NTLVELDQHE IRQYLSRLPT KSYKYKSKNK MNATQKRMSS SSNSSSNSTS
     PLGSPSNLNS NTDDPILLPT NRIIISNDSN FDSKHKVNFI DNIILESGEL WRKWLWSEMI
     DDN