位置:首页 > 蛋白库 > OCA5_KLULA
OCA5_KLULA
ID   OCA5_KLULA              Reviewed;         530 AA.
AC   Q6CS52;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; OrderedLocusNames=KLLA0D03861g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CR382124; CAH00333.1; -; Genomic_DNA.
DR   RefSeq; XP_453237.1; XM_453237.1.
DR   AlphaFoldDB; Q6CS52; -.
DR   STRING; 28985.XP_453237.1; -.
DR   PRIDE; Q6CS52; -.
DR   EnsemblFungi; CAH00333; CAH00333; KLLA0_D03861g.
DR   GeneID; 2892864; -.
DR   KEGG; kla:KLLA0_D03861g; -.
DR   eggNOG; ENOG502QVXN; Eukaryota.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   InParanoid; Q6CS52; -.
DR   OMA; LGPDIFW; -.
DR   Proteomes; UP000000598; Chromosome D.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..530
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408212"
FT   DOMAIN          58..319
FT                   /note="Rab-GAP TBC"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          467..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        473..491
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   530 AA;  62300 MW;  6A90ED32BC5E94A4 CRC64;
     MPLKPSSSHS ERKNRLHLHA SSRNAKQQEW NRELVTLFIK LLNENDHASL ALVARNAGVP
     PQLRPAVWPT LLKYHPMVIS PNIMSNTLVF KDDENEAELR YFPEDRSEED ISELMENDLN
     KYFQVRNSVP VSAEIQEIKS LLKECVWQFL RKWNKICKYE SGLIWIALGL AEWCPLKNND
     DLVLAGRKHH HHNSCLRHLY EEYPIPDELL NQLPDTEFDF AAIYERLVLV LFHAPALDEK
     PDKSNYHLLK SGNLNQQSQL FFKVFAKTLP ELYQPITDEG ALQGSKKATW LYWWIKCCGC
     RVLHRQDRGR VWDVLLGWRP RPESINYYLE YNHKSFESIY PPELKLSSEI FHKICKCEHD
     EFWFPDLMSL RLGQNGLNQD EDVIRELIRR NKYGDDGHTT ETQENEIPYS LLNPHAELLF
     IYVAIMQHNE FKLLEFEETE ITEFLNNVPL ISKFDDYNFK KMYEDDDISG SSTDTDESNA
     SGIRPSSSNH MMIEVGTDDK TAHSFDDIYQ QAGDIWRNWA WQEMEEFIEE
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024