ID   OCA5_KOMPG              Reviewed;         674 AA.
AC   C4R492;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; OrderedLocusNames=PAS_chr3_1177;
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864;
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
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DR   EMBL; FN392321; CAY70378.1; -; Genomic_DNA.
DR   RefSeq; XP_002492557.1; XM_002492512.1.
DR   AlphaFoldDB; C4R492; -.
DR   STRING; 644223.C4R492; -.
DR   EnsemblFungi; CAY70378; CAY70378; PAS_chr3_1177.
DR   GeneID; 8199473; -.
DR   KEGG; ppa:PAS_chr3_1177; -.
DR   eggNOG; ENOG502QVXN; Eukaryota.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   InParanoid; C4R492; -.
DR   OMA; LGPDIFW; -.
DR   Proteomes; UP000000314; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   SUPFAM; SSF47923; SSF47923; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..674
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408216"
FT   DOMAIN          77..411
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          102..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          590..651
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        106..123
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..145
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        622..642
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   674 AA;  77174 MW;  5B6AED390B13017B CRC64;
     MSQNSSIGKG NQSPPLFDLY EGHQEGSETE ATSAAKYPNL FKSETTITDL PELVKLLHKF
     LETKNVTGLA LIARQKGLPP SMRAKVWPLL LRTHPFVLKP YITSDDDDGD DVDGEEEEQE
     DDLHSSTPDN STTSSNDTEG SDNEYPSSIP IHRIRSELQR YTIRSNYNKD IIMSLSPQVR
     QLFEVQEQIF HTIERAVARF LKKWGSIVHY DPGLVWLGLA LAEWIPPLPE YSYILCGREH
     VARNGTKLRD INDDNFQRLY VNDDISSIIL NYQSEDAKFS INENKEPSND KSNKHQKNLS
     FAELYERMVL VVLHSPEQSD VVETDSMHER TNNILQTIPT KGGSISERVS FFLHCFRHLL
     PELSNYFSEE DILNGYNNSD EWVIWWLKWG GARAWSRFDR GRVWDYLLGW RNGLPANPNS
     KTEILRHQEE LEEVRSCLDS HTLELLGPDL FWNPLVKEDV DSTKKPEPES CALSRKESLK
     SMLSTLSLTN NTALEWSSSS VGLDERERQS NHRDTLLQIP YSQIDPHSAL VFIAVAFLKS
     KEFALLELES TEILEFLNKS SSLKFNGFQS LISDPKWDTE DADVRKIMDS YNNSPEDRDV
     RHLPSSGISY TAEKDSKTNS KGKRAFSPSP PSDLSLTGRY RSQPKRSPRG IENVITEAGE
     LWRKWSWQEL VEDN