ID   OCA5_PICGU              Reviewed;         561 AA.
AC   A5DG41;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; ORFNames=PGUG_02242;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
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DR   EMBL; CH408156; EDK38144.2; -; Genomic_DNA.
DR   RefSeq; XP_001486571.1; XM_001486521.1.
DR   AlphaFoldDB; A5DG41; -.
DR   STRING; 4929.XP_001486571.1; -.
DR   PRIDE; A5DG41; -.
DR   EnsemblFungi; EDK38144; EDK38144; PGUG_02242.
DR   GeneID; 5128500; -.
DR   KEGG; pgu:PGUG_02242; -.
DR   VEuPathDB; FungiDB:PGUG_02242; -.
DR   eggNOG; ENOG502QVXN; Eukaryota.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   InParanoid; A5DG41; -.
DR   OMA; LGPDIFW; -.
DR   OrthoDB; 467078at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..561
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408215"
FT   DOMAIN          50..330
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00163"
FT   REGION          399..434
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          498..529
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        509..529
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   561 AA;  65269 MW;  3DEB0FB6638DEB19 CRC64;
     MSEQSPRDPV AASENRKPSF RFDADIFKLC TRYLEENNYH GLALIARQKG LPPFLRLRIW
     PILLKHHPFV LNPFLQPDND VLNKPKHDSD QDDRAEGQLN DEDIRFNIKK DLKKYVQRLK
     YNSSPDINEI EMEMLEVLEK AIFKFVKKWG KIIKYDQAIT WIALGLAEWL PPIENTHWVL
     IGRDVSSSDN LYITNIMDEY STYIENVPDL EDYLNDVIAS PQMKFSDVFE RLVLVLLHSP
     ENRTRSPSSK VNKTTLPLNG GTIEDRVSFF IYCLRKLLPE LSDYFQEEQI LNKFGSNDDE
     WLIWWLKWCG SKVWSRMDRG RIWDMILGWR LQNPKKSTAY YQDKLKLTKH QLEKLGPDVF
     WSVSQHDEET VDERGEPDEF KKSDSFKDLL HGLSMANISA SSSNTNSPSE STSPLLTPTR
     RSSSSSTSLS EGIDDMNIPF SRLDPHIELV FISLALLKSK EGTLVELDQH EIRQFLSRLP
     TKSYNYTTRY QKYKQMKMEK EKEEDNGNGS VSSEASNSDG GSQIITNDNA NSRRYDFMDN
     VVNEAGELWR KWFWSEAVDN E