ID   OCA5_YEAS1              Reviewed;         679 AA.
AC   B3LS90;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; ORFNames=SCRG_04674;
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a;
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for replication of brome mosaic virus (BMV), a
CC       positive-strand RNA virus. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH408053; EDV09021.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LS90; -.
DR   EnsemblFungi; EDV09021; EDV09021; SCRG_04674.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..679
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408217"
FT   DOMAIN          50..441
FT                   /note="Rab-GAP TBC"
FT   REGION          135..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          524..544
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   679 AA;  77756 MW;  AA2C5434FFDD881A CRC64;
     MHDKKSPMAN SHYLKNLKQQ FRNKNLIETT IHLVKCNDHD SLAFLARTYG VPPQLRHVVW
     PILLKYHPMC ISPNITSNTI SWDPITNDFI LNDPFLKSKA PTDKQDKSDD ENILPYDIES
     IILHDLKKYF HSRSNPAGSS SNANTTNIAT PTPVSSSDAS TISSMEVLSP SLDYEFQIIE
     TLKNAIVKFL LKWSKIFKYE SGLAWIALGL AEWYPIYPYE TMSPFNETHS FYEVEDYVVL
     SGRKHALLST NNGNNGNSNS SSNNTNNNNT NITSGMHNLS INTNTSLHNS PYISHTLSYL
     YKEYPLPFEL RSKLPTKPIF SFSALFERLA LVILHCPDTI LAHKQLKNDS NASSSSKANS
     NFNTNYFPII SGGDLSFQTQ VFFKVFSSIL PELYQPLTEE SSLQPSSSRN SWIYWWLKCS
     GAKALQRQDR GRVWDLLLGW RPKPNMDTIN FFLNYNDKKM DHLYHDTPQC DNEQYWMKDW
     IALYNNDPFW FPDLDSMALG SKKFPYDYSV FKELILRNRY GGTQSKAQKD NTVPSPGSDS
     NDKSELKLPF SSIDPHMQLI FIFIAILQFN EFKLLEFEEA EISEFLNNVP LLTKFDDSSY
     RKLYENTESS ITSLPSSPTT STMASLQSSS NSSAHISNYH MLIEVGNDAK ASHCFDDLLN
     MAGDIWRKWL WRELEESSL