OCA5_YEAS7
ID OCA5_YEAS7 Reviewed; 679 AA.
AC A6ZSM1;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN Name=OCA5; ORFNames=SCY_2355;
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789;
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- FUNCTION: Required for replication of brome mosaic virus (BMV), a
CC positive-strand RNA virus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
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DR EMBL; AAFW02000081; EDN62462.1; -; Genomic_DNA.
DR AlphaFoldDB; A6ZSM1; -.
DR EnsemblFungi; EDN62462; EDN62462; SCY_2355.
DR HOGENOM; CLU_028817_0_0_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47923; SSF47923; 1.
PE 3: Inferred from homology;
KW Cytoplasm.
FT CHAIN 1..679
FT /note="Oxidant-induced cell-cycle arrest protein 5"
FT /id="PRO_0000408220"
FT DOMAIN 50..441
FT /note="Rab-GAP TBC"
FT REGION 135..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 679 AA; 77756 MW; AA2C5434FFDD881A CRC64;
MHDKKSPMAN SHYLKNLKQQ FRNKNLIETT IHLVKCNDHD SLAFLARTYG VPPQLRHVVW
PILLKYHPMC ISPNITSNTI SWDPITNDFI LNDPFLKSKA PTDKQDKSDD ENILPYDIES
IILHDLKKYF HSRSNPAGSS SNANTTNIAT PTPVSSSDAS TISSMEVLSP SLDYEFQIIE
TLKNAIVKFL LKWSKIFKYE SGLAWIALGL AEWYPIYPYE TMSPFNETHS FYEVEDYVVL
SGRKHALLST NNGNNGNSNS SSNNTNNNNT NITSGMHNLS INTNTSLHNS PYISHTLSYL
YKEYPLPFEL RSKLPTKPIF SFSALFERLA LVILHCPDTI LAHKQLKNDS NASSSSKANS
NFNTNYFPII SGGDLSFQTQ VFFKVFSSIL PELYQPLTEE SSLQPSSSRN SWIYWWLKCS
GAKALQRQDR GRVWDLLLGW RPKPNMDTIN FFLNYNDKKM DHLYHDTPQC DNEQYWMKDW
IALYNNDPFW FPDLDSMALG SKKFPYDYSV FKELILRNRY GGTQSKAQKD NTVPSPGSDS
NDKSELKLPF SSIDPHMQLI FIFIAILQFN EFKLLEFEEA EISEFLNNVP LLTKFDDSSY
RKLYENTESS ITSLPSSPTT STMASLQSSS NSSAHISNYH MLIEVGNDAK ASHCFDDLLN
MAGDIWRKWL WRELEESSL