ID   OCA5_YEAS8              Reviewed;         679 AA.
AC   C8ZA35;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Oxidant-induced cell-cycle arrest protein 5;
GN   Name=OCA5; ORFNames=EC1118_1H21_0243g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: Required for replication of brome mosaic virus (BMV), a
CC       positive-strand RNA virus. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OCA5 family. {ECO:0000305}.
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DR   EMBL; FN393072; CAY80251.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8ZA35; -.
DR   EnsemblFungi; CAY80251; CAY80251; EC1118_1H21_0243g.
DR   HOGENOM; CLU_028817_0_0_1; -.
DR   Proteomes; UP000000286; Chromosome VIII, Scaffold EC1118_1H21.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 1.
PE   3: Inferred from homology;
KW   Cytoplasm.
FT   CHAIN           1..679
FT                   /note="Oxidant-induced cell-cycle arrest protein 5"
FT                   /id="PRO_0000408221"
FT   DOMAIN          50..441
FT                   /note="Rab-GAP TBC"
FT   REGION          135..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          524..544
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   679 AA;  77767 MW;  A8D386C9D00F77CA CRC64;
     MHDKKSPMAN SHYLKNLKQQ FRNKNLIETT IHLVKCNDHD SLAFLARTYG VPPQLRHVVW
     PILLKYHPMC ISPNITSNTI SWDPITNDFI LNDPFLKSKA PTDKQDKSDD ENILPYDIES
     IILHDLKKYF HSRSNPAGSS SNANTTNIAT PTPVSSSDAS TISSMEVLSP SLDYEFQIIE
     TLKNAIVKFL LKWSKIFKYE SGLAWIALGL AEWYPIYPYE TMSPFNETHS FYEVEDYVVL
     SGRKHALLST NNGNNGNSNS SSNNTNNNNT NITSGMHNLS INTNTSLHNS PYISHTLSYL
     YKEYPLPFEL RSKLPTKPIF SFSALFERLA LVILHCPDTI LAHKQLKNDS NASSSSKANS
     NFNTNYFPII SGGDLSFQTQ VFFKVFSSIL PELYQPLTEE SSLQPSSSRN SWIYWWLKCS
     GAKALQRQDR GRVWDLLLGW RPKPNMDTIN FFLNYNDKKM DHLYHDTPQC DNEQYWMKDW
     IALYNNDPFW FPDLDSMALG SKKFPYDYSV FKELILRNRY GGTQSKAQKD NTVPSPGSDS
     NDKSELKLPF SSIDPHMQLI FIFIAILQFN EFKLLEFEEA EIPEFLNNVP LLTKFDDSSY
     RKLYENTESS ITSLPSSPTT STMASLQSSS NSSAHISNYH MLIEVGNDAK ASHCFDDLLN
     MAGDIWRKWL WRELEESSL