OCAD1_DANRE
ID OCAD1_DANRE Reviewed; 266 AA.
AC Q6NYD7; Q7ZW99;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=OCIA domain-containing protein 1;
GN Name=ociad1; ORFNames=si:ch211-14g4.3, zgc:56639;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OCIAD1 family. {ECO:0000305}.
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DR EMBL; BX323889; CAI11614.1; -; Genomic_DNA.
DR EMBL; BC049514; AAH49514.1; -; mRNA.
DR EMBL; BC066633; AAH66633.1; -; mRNA.
DR RefSeq; NP_956596.1; NM_200302.2.
DR AlphaFoldDB; Q6NYD7; -.
DR STRING; 7955.ENSDARP00000094142; -.
DR PaxDb; Q6NYD7; -.
DR PRIDE; Q6NYD7; -.
DR Ensembl; ENSDART00000103365; ENSDARP00000094142; ENSDARG00000052334.
DR Ensembl; ENSDART00000141510; ENSDARP00000112683; ENSDARG00000052334.
DR GeneID; 393272; -.
DR KEGG; dre:393272; -.
DR CTD; 54940; -.
DR ZFIN; ZDB-GENE-040426-1100; ociad1.
DR eggNOG; ENOG502RXQR; Eukaryota.
DR GeneTree; ENSGT00530000063690; -.
DR HOGENOM; CLU_083038_0_0_1; -.
DR InParanoid; Q6NYD7; -.
DR OMA; AGKMSYM; -.
DR OrthoDB; 1322104at2759; -.
DR PhylomeDB; Q6NYD7; -.
DR TreeFam; TF327106; -.
DR ChiTaRS; ociad1; zebrafish.
DR PRO; PR:Q6NYD7; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 20.
DR Bgee; ENSDARG00000052334; Expressed in early embryo and 27 other tissues.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR InterPro; IPR040187; OCAD1/2.
DR InterPro; IPR009764; OCIA_dom.
DR PANTHER; PTHR13336; PTHR13336; 1.
DR Pfam; PF07051; OCIA; 1.
PE 2: Evidence at transcript level;
KW Endosome; Reference proteome.
FT CHAIN 1..266
FT /note="OCIA domain-containing protein 1"
FT /id="PRO_0000299386"
FT DOMAIN 1..114
FT /note="OCIA"
FT REGION 127..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..191
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..266
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 122
FT /note="R -> H (in Ref. 2; AAH49514)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 266 AA; 29733 MW; 7CC709F02BC246A0 CRC64;
MSQASSGFTP AAQVQHGSSK GAFNSAYIPT EEEKRVFREC NSESFWYRSL PFSAIAVGIT
QVLVAKGMLS PSPRFGALPK IAFAGIFGYI GGKMSYVRVC QEKFMKLENS PLGEALRQGR
LRHVSSEMNQ PDFDPNSSES QQPGSESVQQ PATEVSSATE SYSSYTSDYT YSTPSQSYET
TPFSSGFSDS GPANIRDDLP SQAPLYMEED VPKRKPVLYE ELRNKNRENY EVTLPQKNQT
QMKPQMEVMQ PKKEAKKNKY GDSWEE
