ID   OCP1_CALMC              Reviewed;           4 AA.
AC   P58648;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 1.
DT   07-OCT-2020, entry version 41.
DE   RecName: Full=Cardioactive peptide Ocp-1/Ocp-2;
OS   Callistoctopus minor (Octopus) (Octopus minor).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae;
OC   Callistoctopus.
OX   NCBI_TaxID=515824;
RN   [1]
RP   PROTEIN SEQUENCE, D-AMINO ACID AT PHE-2, SYNTHESIS, MASS SPECTROMETRY, AND
RP   CHARACTERIZATION.
RC   TISSUE=Brain;
RX   PubMed=10876044; DOI=10.1016/s0196-9781(00)00201-1;
RA   Iwakoshi E., Hisada M., Minakata H.;
RT   "Cardioactive peptides isolated from the brain of a Japanese octopus,
RT   Octopus minor.";
RL   Peptides 21:623-630(2000).
CC   -!- FUNCTION: Cardioactive; has both positive chronotropic and inotropic
CC       effects on the heart. Ocp-2 is a 1000 time less active than Ocp-1.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- PTM: Ocp-2 has L-Phe instead of D-Phe.
CC   -!- MASS SPECTROMETRY: Mass=395.2; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:10876044};
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   D-amino acid; Direct protein sequencing; Hormone; Secreted.
FT   PEPTIDE         1..4
FT                   /note="Cardioactive peptide Ocp-1/Ocp-2"
FT                   /id="PRO_0000044179"
FT   MOD_RES         2
FT                   /note="D-phenylalanine; in form Ocp-1"
FT                   /evidence="ECO:0000269|PubMed:10876044"
SQ   SEQUENCE   4 AA;  394 MW;  6AA879C810000000 CRC64;
     GFGD