ODA1_CHLRE
ID ODA1_CHLRE Reviewed; 552 AA.
AC A8JF70; Q8LGS5;
DT 03-APR-2013, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=Outer dynein arm protein 1;
DE AltName: Full=Docking complex component 2;
GN Name=ODA1; Synonyms=DCC2; ORFNames=CHLREDRAFT_132719;
OS Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX NCBI_TaxID=3055;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 60-75; 286-305 AND 460-481,
RP FUNCTION, SUBCELLULAR LOCATION, IDENTIFICATION IN THE OUTER DYNEIN ARM
RP COMPLEX, AND DISRUPTION PHENOTYPE.
RX PubMed=11907279; DOI=10.1091/mbc.01-04-0201;
RA Takada S., Wilkerson C.G., Wakabayashi K., Kamiya R., Witman G.B.;
RT "The outer dynein arm-docking complex: composition and characterization of
RT a subunit (oda1) necessary for outer arm assembly.";
RL Mol. Biol. Cell 13:1015-1029(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CC-503;
RX PubMed=17932292; DOI=10.1126/science.1143609;
RA Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT "The Chlamydomonas genome reveals the evolution of key animal and plant
RT functions.";
RL Science 318:245-250(2007).
CC -!- FUNCTION: Component of the outer dynein arm complex required for
CC assembly of the outer dynein arm-docking complex (ODA-DC) and the outer
CC dynein arm onto the doublet microtubule. {ECO:0000269|PubMed:11907279}.
CC -!- SUBUNIT: Component of the outer dynein arm complex.
CC {ECO:0000269|PubMed:11907279}.
CC -!- INTERACTION:
CC A8JF70; A8IPZ5: ODA3; NbExp=3; IntAct=EBI-8534735, EBI-8534794;
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000269|PubMed:11907279}.
CC -!- DISRUPTION PHENOTYPE: Impaired motility and outer dynein arm defects.
CC {ECO:0000269|PubMed:11907279}.
CC -!- SIMILARITY: Belongs to the ODA1/DCC2 family. {ECO:0000305}.
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DR EMBL; AY039618; AAK72125.1; -; mRNA.
DR EMBL; DS496174; EDO97433.1; -; Genomic_DNA.
DR RefSeq; XP_001701436.1; XM_001701384.1.
DR PDB; 6U42; EM; 3.40 A; 7T/7U=1-552.
DR PDB; 7KZM; EM; 7.50 A; Y/Y1=1-552.
DR PDB; 7KZO; EM; 3.30 A; Y/Y1=1-552.
DR PDBsum; 6U42; -.
DR PDBsum; 7KZM; -.
DR PDBsum; 7KZO; -.
DR AlphaFoldDB; A8JF70; -.
DR SMR; A8JF70; -.
DR IntAct; A8JF70; 3.
DR MINT; A8JF70; -.
DR STRING; 3055.EDO97433; -.
DR PaxDb; A8JF70; -.
DR PRIDE; A8JF70; -.
DR EnsemblPlants; PNW71716; PNW71716; CHLRE_16g666150v5.
DR GeneID; 5726980; -.
DR Gramene; PNW71716; PNW71716; CHLRE_16g666150v5.
DR KEGG; cre:CHLRE_16g666150v5; -.
DR eggNOG; ENOG502QSIU; Eukaryota.
DR HOGENOM; CLU_027546_3_1_1; -.
DR InParanoid; A8JF70; -.
DR OMA; CYKDTIC; -.
DR OrthoDB; 648380at2759; -.
DR GO; GO:0036157; C:outer dynein arm; IDA:UniProtKB.
DR GO; GO:0060294; P:cilium movement involved in cell motility; IMP:GO_Central.
DR GO; GO:0036158; P:outer dynein arm assembly; IMP:UniProtKB.
PE 1: Evidence at protein level;
KW 3D-structure; Cell projection; Cilium; Coiled coil; Cytoplasm;
KW Cytoskeleton; Direct protein sequencing.
FT CHAIN 1..552
FT /note="Outer dynein arm protein 1"
FT /id="PRO_0000421993"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 28..59
FT /evidence="ECO:0000255"
FT COILED 120..260
FT /evidence="ECO:0000255"
FT COILED 331..395
FT /evidence="ECO:0000255"
FT CONFLICT 492
FT /note="T -> M (in Ref. 1; AAK72125)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 552 AA; 62204 MW; 1C4CD4F2A3CAE862 CRC64;
MPSADATRGG GSAGSMGKGT LGAGDTLGHK SVLDKQRAAI EKLRAQNEQL KTELLLENKF
SVRPGDPFAQ ALINRLQDEG DMLARKIVLE MRKTKMLDQQ LSEMGSTLTT TRNNMGGIFS
AKEQSTAVQK RIKLLENRLE KAYVKYNQSI THNKQLRESI NNLRRERIMF ESIQSNLERE
LAKLKRDMAD MIQQANGAFE AREKAIGEMN ALKAQADKEQ QGFEEEWRQL TTIIEEDKKE
RERARAQELA MRERETQELL KMGTLSSAEK KKRITKGSWN VGYNKAMAQN VAAEKVEMYG
QAFKRIQDAT GIEDIDQLVN TFLAAEDQNY TLFNYVNEVN QEIEKLEDQI NIMRGEINKY
RETGRELDMT KSRELTEEEA RLAASEAQSQ LYEKRTDSAL SMTTALKAGI NDLFERIGCN
TPAVRDLLGE EGVTEANLTA YLGIIEQRTN EILQIYAKRK AQQGTDGLAE ALLAQPLTQP
GNRIIIEPPS TTQEEEVEGL EPEPVEEDRP LTREHLESKV QRTLPRKLET AIKVRPAGAD
ATGGKRGSPT RR
