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ODF2L_BOVIN
ID   ODF2L_BOVIN             Reviewed;         548 AA.
AC   Q0VBY1;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Protein BCAP {ECO:0000250|UniProtKB:Q9ULJ1};
DE   AltName: Full=Basal body centriole-associated protein;
DE   AltName: Full=Outer dense fiber protein 2-like;
GN   Name=ODF2L; Synonyms=BCAP;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a suppressor of ciliogenesis, specifically, the
CC       initiation of ciliogenesis. {ECO:0000250|UniProtKB:Q9ULJ1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250|UniProtKB:Q9ULJ1}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, centrosome, centriole
CC       {ECO:0000250|UniProtKB:Q9ULJ1}. Cytoplasm, cytoskeleton, microtubule
CC       organizing center, centrosome, centriolar satellite
CC       {ECO:0000250|UniProtKB:Q9ULJ1}. Cytoplasm, cytoskeleton, cilium basal
CC       body {ECO:0000250|UniProtKB:Q9ULJ1}. Note=Localizes to centrioles in
CC       proliferative cells and basal bodies in ciliated cells. Disappears
CC       during ciliogenesis but reappears, albeit at a lower levels once
CC       ciliogenesis has completed. {ECO:0000250|UniProtKB:Q9ULJ1}.
CC   -!- SIMILARITY: Belongs to the ODF2 family. {ECO:0000305}.
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DR   EMBL; BC120451; AAI20452.1; -; mRNA.
DR   RefSeq; NP_001069461.1; NM_001075993.1.
DR   AlphaFoldDB; Q0VBY1; -.
DR   SMR; Q0VBY1; -.
DR   STRING; 9913.ENSBTAP00000017157; -.
DR   PaxDb; Q0VBY1; -.
DR   PRIDE; Q0VBY1; -.
DR   GeneID; 533508; -.
DR   KEGG; bta:533508; -.
DR   CTD; 57489; -.
DR   eggNOG; ENOG502R83P; Eukaryota.
DR   InParanoid; Q0VBY1; -.
DR   OrthoDB; 328077at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0034451; C:centriolar satellite; ISS:UniProtKB.
DR   GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0036064; C:ciliary basal body; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:1902018; P:negative regulation of cilium assembly; ISS:UniProtKB.
DR   InterPro; IPR026102; BCAP.
DR   InterPro; IPR026099; Odf2-rel.
DR   PANTHER; PTHR23162; PTHR23162; 3.
DR   PANTHER; PTHR23162:SF7; PTHR23162:SF7; 3.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium biogenesis/degradation; Coiled coil; Cytoplasm;
KW   Cytoskeleton; Reference proteome.
FT   CHAIN           1..548
FT                   /note="Protein BCAP"
FT                   /id="PRO_0000308908"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          98..177
FT                   /evidence="ECO:0000255"
FT   COILED          206..282
FT                   /evidence="ECO:0000255"
FT   COILED          394..506
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   548 AA;  63862 MW;  D230C7E0D7129AC5 CRC64;
     MEETANDGSH SEELFSHFES RSEKEGLPQD ASESHLSCLK QDIQNEKTEL EALFKEAELA
     TCSAELLLPL FKDTIEEISF ENRGESLSNL LEKLTDNERE NINLKNKVLE KETYIQELSS
     LFQNEKANAL KASRFSQSVK VVHERLQSQI HKKEAENEKL KEHIKSLETQ ISEWNLQLKK
     NKYEAVAMKE SSRQKTIALK KASKIYKQRI EHFTGDMENL TSQIREQEAK LSETVSASNA
     WKSHYEKIVI EKTELEVQIE TMKKQIINLL EDLKKMEEHG KISCEEILRK LHSIEYENET
     LNLENTKLKT TLATLKDEIA SVENELLELQ EVEKQQKTLI EVYKTQIQKV QEAAEMVKSR
     CKNLLQENSL ITKNKNKKLK KVDENHSLLT KLSLEEENYL IQLKCENLKQ KLEQMDAENK
     ELEKKLANQE ECLKHSNLKF KEKSAEYTAL ARQLEAALEE GRQKVSEEIE KMSSRERALQ
     VKIVDLENEL RKKNEEQNQL VCKMNSKAQH QEVCLKEIQH SLEKSENQNE SIKNYLQFLK
     TSYVTMFG
 
 
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