ID   ODF2L_XENLA             Reviewed;         641 AA.
AC   Q08B20;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 36.
DE   RecName: Full=Protein BCAP {ECO:0000250|UniProtKB:Q9ULJ1};
DE   AltName: Full=Basal body centriole-associated protein;
DE   AltName: Full=Outer dense fiber protein 2-like;
GN   Name=odf2l; Synonyms=bcap;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a suppressor of ciliogenesis, specifically, the
CC       initiation of ciliogenesis. {ECO:0000250|UniProtKB:Q9ULJ1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250|UniProtKB:Q9ULJ1}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, centrosome, centriole
CC       {ECO:0000250|UniProtKB:Q9ULJ1}. Cytoplasm, cytoskeleton, microtubule
CC       organizing center, centrosome, centriolar satellite
CC       {ECO:0000250|UniProtKB:Q9ULJ1}. Cytoplasm, cytoskeleton, cilium basal
CC       body {ECO:0000250|UniProtKB:Q9ULJ1}. Note=Localizes to centrioles in
CC       proliferative cells and basal bodies in ciliated cells. Disappears
CC       during ciliogenesis but reappears, albeit at a lower levels once
CC       ciliogenesis has completed. {ECO:0000250|UniProtKB:Q9ULJ1}.
CC   -!- SIMILARITY: Belongs to the ODF2 family. {ECO:0000305}.
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DR   EMBL; BC124909; AAI24910.1; -; mRNA.
DR   RefSeq; NP_001116356.1; NM_001122884.1.
DR   AlphaFoldDB; Q08B20; -.
DR   SMR; Q08B20; -.
DR   DNASU; 733263; -.
DR   GeneID; 733263; -.
DR   KEGG; xla:733263; -.
DR   CTD; 733263; -.
DR   Xenbase; XB-GENE-948656; odf2l.L.
DR   OrthoDB; 328077at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 733263; Expressed in gastrula and 19 other tissues.
DR   GO; GO:0034451; C:centriolar satellite; ISS:UniProtKB.
DR   GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0036064; C:ciliary basal body; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:1902018; P:negative regulation of cilium assembly; ISS:UniProtKB.
DR   InterPro; IPR026102; BCAP.
DR   InterPro; IPR026099; Odf2-rel.
DR   PANTHER; PTHR23162; PTHR23162; 2.
DR   PANTHER; PTHR23162:SF7; PTHR23162:SF7; 2.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium biogenesis/degradation; Coiled coil; Cytoplasm;
KW   Cytoskeleton; Reference proteome.
FT   CHAIN           1..641
FT                   /note="Protein BCAP"
FT                   /id="PRO_0000308911"
FT   COILED          83..144
FT                   /evidence="ECO:0000255"
FT   COILED          191..270
FT                   /evidence="ECO:0000255"
FT   COILED          299..375
FT                   /evidence="ECO:0000255"
FT   COILED          487..599
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   641 AA;  74208 MW;  36F67F7ED04485B0 CRC64;
     MKTPTSTIQT NAATATHGNL VSTSNANFSE HMDERSSVLT QDTQEFLTDL LNRQKTRLNE
     LSSHLSSMAH SETFLSSLKS SMHWPVEELT CDKVVTLLTK LKDTDVAANS VETLIEKLKD
     SSRGILRADN VSSLDAIDIS KQNDLLWKEL ETFRHIRGIL ESFLQTHYSK SSRLINQESV
     EVLMGQLLEH EKDNLRLREQ VVEKETKVED LLHLIQQEKD TAVKSNQVSR STEATHIRLQ
     NLVKRKETEN QQIVTQIQSL AAVISGRKLE IEDLRREITH LKEKQTFEKE GLKKAFRVQK
     QKVDNFQDVM ENLNTQIKKK ETELSEVHSS CSIWKDHHDS AVETKTRLEV QHESLTKQIS
     DHLKLIKTMD EEREQSKEEN AEKISAIILE NAHFSEENVK LKASIAALES ETVLVNSELL
     EVREKASQQK HFAEQYENQV QKLQEELNKL KEKFKDVLTK KKEILENKAS ENKKVDTNDY
     FLGNESFKLE NNRIERKCEE IRIKLEKMIM HNEQLESKLK GQERDLQRSE VELEGKAKEC
     STLMRLLENA VEAGNKQISE ENNKVLSKEL ALQRKLQSLE SELKRKRAEH KQLGCTLNAF
     EKTHNLRLEE IRHSLEMTES RNKSIQSYVQ FLKTSYAAMF E