ID   ODFP1_MOUSE             Reviewed;         247 AA.
AC   Q61999;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Outer dense fiber protein 1;
GN   Name=Odf1; Synonyms=Odfp;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RX   PubMed=7789171; DOI=10.1159/000134033;
RA   Hoyer-Fender S., Burfeind P., Hameister H.;
RT   "Sequence of mouse Odf1 cDNA and its chromosomal localization: extension of
RT   the linkage group between human chromosome 8 and mouse chromosome 15.";
RL   Cytogenet. Cell Genet. 70:200-204(1995).
CC   -!- FUNCTION: Component of the outer dense fibers (ODF) of spermatozoa. ODF
CC       are filamentous structures located on the outside of the axoneme in the
CC       midpiece and principal piece of the mammalian sperm tail and may help
CC       to maintain the passive elastic structures and elastic recoil of the
CC       sperm tail.
CC   -!- SUBUNIT: Interacts (via leucine zipper motif) with TCP11 (By
CC       similarity). Interacts with SPAG4 (By similarity). Interacts with KLC3
CC       (By similarity). {ECO:0000250|UniProtKB:P21769,
CC       ECO:0000250|UniProtKB:Q14990}.
CC   -!- DOMAIN: The C-terminal contains many C-X-P repeats.
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DR   EMBL; X79446; CAA55965.1; -; mRNA.
DR   PIR; I48699; I48699.
DR   AlphaFoldDB; Q61999; -.
DR   SMR; Q61999; -.
DR   STRING; 10090.ENSMUSP00000080632; -.
DR   iPTMnet; Q61999; -.
DR   PhosphoSitePlus; Q61999; -.
DR   PaxDb; Q61999; -.
DR   PRIDE; Q61999; -.
DR   ProteomicsDB; 293485; -.
DR   MGI; MGI:97424; Odf1.
DR   eggNOG; ENOG502S68A; Eukaryota.
DR   InParanoid; Q61999; -.
DR   PRO; PR:Q61999; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q61999; protein.
DR   GO; GO:0001520; C:outer dense fiber; IDA:MGI.
DR   GO; GO:0019904; F:protein domain specific binding; ISO:MGI.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   CDD; cd06482; ACD_HspB10; 1.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR037552; ODF1_ACD.
DR   InterPro; IPR037389; ODFP.
DR   PANTHER; PTHR17125; PTHR17125; 1.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; Phosphoprotein; Reference proteome;
KW   Repeat; Spermatogenesis.
FT   CHAIN           1..247
FT                   /note="Outer dense fiber protein 1"
FT                   /id="PRO_0000058025"
FT   REPEAT          34..38
FT                   /note="1"
FT   REPEAT          74..78
FT                   /note="2"
FT   REGION          34..78
FT                   /note="2 X 5 AA repeats of [RC]-C-L-C-D"
FT   REGION          195..235
FT                   /note="C-X-P repeat region"
FT   MOD_RES         5
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         10
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         64
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         87
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         108
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         109
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         137
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         153
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         175
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         180
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
SQ   SEQUENCE   247 AA;  27539 MW;  821EB57C2D67E458 CRC64;
     MAALSCLLDS VRRDIKKVDR ELRQLRCIDE ISSRCLCDLY MHPYCCCDLH PYPYCLCYSK
     RSRSCGLCDL YYPCCLCDYK LYCLRPSLRS LERLRRTTNR ILASSCCSSN ILGSVNVCGF
     EPDQVKVRVK DGKVCVSAER ENRYDCLGSK KYSYMNICKE FSLPPCVDEK DVTYSYGLGS
     CVKIESPCYP CTSPCNPCNP CSPCSPCAPC ACGPCGPCGP CGPCGPCDPC NPCYPCGSRF
     SCRKMIL