ID   ODFP1_PIG               Reviewed;         262 AA.
AC   Q29077;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Outer dense fiber protein 1;
GN   Name=ODF1; Synonyms=ODFP;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Testis;
RX   PubMed=7576240; DOI=10.1515/bchm3.1995.376.7.431;
RA   Kim Y., Adham I.M., Haack T., Kremling H., Engel W.;
RT   "Molecular cloning and characterization of the bovine and porcine outer
RT   dense fibers cDNA and organization of the bovine gene.";
RL   Biol. Chem. Hoppe-Seyler 376:431-435(1995).
CC   -!- FUNCTION: Component of the outer dense fibers (ODF) of spermatozoa. ODF
CC       are filamentous structures located on the outside of the axoneme in the
CC       midpiece and principal piece of the mammalian sperm tail and may help
CC       to maintain the passive elastic structures and elastic recoil of the
CC       sperm tail.
CC   -!- SUBUNIT: Interacts (via leucine zipper motif) with TCP11 (By
CC       similarity). Interacts with SPAG4 (By similarity). Interacts with KLC3
CC       (By similarity). {ECO:0000250|UniProtKB:P21769,
CC       ECO:0000250|UniProtKB:Q14990}.
CC   -!- DOMAIN: The C-terminal contains many C-X-P repeats.
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DR   EMBL; X69513; CAA49264.1; -; mRNA.
DR   PIR; S56100; S56100.
DR   RefSeq; NP_999420.1; NM_214255.2.
DR   AlphaFoldDB; Q29077; -.
DR   SMR; Q29077; -.
DR   STRING; 9823.ENSSSCP00000006466; -.
DR   PaxDb; Q29077; -.
DR   Ensembl; ENSSSCT00000006645; ENSSSCP00000006466; ENSSSCG00000006056.
DR   Ensembl; ENSSSCT00005063960; ENSSSCP00005039527; ENSSSCG00005039970.
DR   Ensembl; ENSSSCT00015025367; ENSSSCP00015009906; ENSSSCG00015019215.
DR   Ensembl; ENSSSCT00025086988; ENSSSCP00025037883; ENSSSCG00025063513.
DR   Ensembl; ENSSSCT00030000431; ENSSSCP00030000249; ENSSSCG00030000286.
DR   Ensembl; ENSSSCT00035018615; ENSSSCP00035006538; ENSSSCG00035014666.
DR   Ensembl; ENSSSCT00040023765; ENSSSCP00040010063; ENSSSCG00040017589.
DR   Ensembl; ENSSSCT00045039806; ENSSSCP00045027713; ENSSSCG00045023274.
DR   Ensembl; ENSSSCT00050029400; ENSSSCP00050012190; ENSSSCG00050021807.
DR   Ensembl; ENSSSCT00055001706; ENSSSCP00055001289; ENSSSCG00055000965.
DR   Ensembl; ENSSSCT00060060228; ENSSSCP00060025819; ENSSSCG00060044407.
DR   Ensembl; ENSSSCT00065013049; ENSSSCP00065005323; ENSSSCG00065009810.
DR   Ensembl; ENSSSCT00070020882; ENSSSCP00070017267; ENSSSCG00070010767.
DR   GeneID; 397489; -.
DR   KEGG; ssc:397489; -.
DR   CTD; 4956; -.
DR   VGNC; VGNC:91016; ODF1.
DR   eggNOG; ENOG502S68A; Eukaryota.
DR   GeneTree; ENSGT00440000038909; -.
DR   InParanoid; Q29077; -.
DR   OMA; LYYPCCL; -.
DR   OrthoDB; 1320934at2759; -.
DR   TreeFam; TF337986; -.
DR   Proteomes; UP000008227; Chromosome 4.
DR   Proteomes; UP000314985; Chromosome 4.
DR   Bgee; ENSSSCG00000006056; Expressed in testis and 6 other tissues.
DR   ExpressionAtlas; Q29077; differential.
DR   Genevisible; Q29077; SS.
DR   GO; GO:0001520; C:outer dense fiber; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   CDD; cd06482; ACD_HspB10; 1.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   InterPro; IPR037552; ODF1_ACD.
DR   InterPro; IPR037389; ODFP.
DR   PANTHER; PTHR17125; PTHR17125; 1.
DR   Pfam; PF00011; HSP20; 1.
DR   SUPFAM; SSF49764; SSF49764; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; Phosphoprotein; Reference proteome;
KW   Repeat; Spermatogenesis.
FT   CHAIN           1..262
FT                   /note="Outer dense fiber protein 1"
FT                   /id="PRO_0000058026"
FT   REPEAT          34..38
FT                   /note="1"
FT   REPEAT          73..77
FT                   /note="2"
FT   REGION          34..77
FT                   /note="2 X 5 AA repeats of [RC]-C-L-C-D"
FT   REGION          209..250
FT                   /note="C-X-P repeat region"
FT   MOD_RES         5
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         10
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         64
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         86
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         122
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         123
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         151
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         167
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         189
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
FT   MOD_RES         194
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P21769"
SQ   SEQUENCE   262 AA;  29526 MW;  663BBACB45F67F15 CRC64;
     MAALSCLLDS VRRDIKKVDR ELRQLRCIDE FSTRCLCDLY MHPYCCCDLH PYPYCLCYSK
     RSRSCGLCDL YPCCLCDVKL YCLRPSLRSL ERKAIRAIED EKRELAKLRR TTNRILASSC
     CSSNILGSVN VCGFEPDQVK VRVKDGKVCV SAERENRYDC LGSKKYSYMN ICKEFSLPPC
     VDEKDVTYSY GLGSCVKIES PCYPCTSPCN PCNPCSPCNP CNPCNPCNPC SPCSPCSPCN
     PCDPCNPCYP CGSRFSCRKM IL