ID   ODFP2_CHICK             Reviewed;         822 AA.
AC   Q5ZKK5;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Outer dense fiber protein 2;
DE   AltName: Full=Cenexin;
DE   AltName: Full=Outer dense fiber of sperm tails protein 2;
GN   Name=ODF2; ORFNames=RCJMB04_10e12;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Seems to be a major component of sperm tail outer dense
CC       fibers (ODF). ODFs are filamentous structures located on the outside of
CC       the axoneme in the midpiece and principal piece of the mammalian sperm
CC       tail and may help to maintain the passive elastic structures and
CC       elastic recoil of the sperm tail (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Self-associates. Associates with microtubules and forms a
CC       fibrillar structure partially linked to the microtubule network (By
CC       similarity). {ECO:0000250|UniProtKB:Q5BJF6}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250|UniProtKB:A3KGV1}. Cell projection,
CC       cilium {ECO:0000250|UniProtKB:A3KGV1}. Cytoplasm, cytoskeleton,
CC       microtubule organizing center, centrosome, centriole
CC       {ECO:0000250|UniProtKB:A3KGV1}. Cytoplasm, cytoskeleton, spindle pole
CC       {ECO:0000250|UniProtKB:A3KGV1}. Cell projection, cilium, flagellum
CC       {ECO:0000250|UniProtKB:A3KGV1}.
CC   -!- SIMILARITY: Belongs to the ODF2 family. {ECO:0000305}.
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DR   EMBL; AJ720079; CAG31738.1; -; mRNA.
DR   RefSeq; NP_001012817.1; NM_001012799.1.
DR   AlphaFoldDB; Q5ZKK5; -.
DR   SMR; Q5ZKK5; -.
DR   STRING; 9031.ENSGALP00000007591; -.
DR   GeneID; 417213; -.
DR   KEGG; gga:417213; -.
DR   CTD; 4957; -.
DR   VEuPathDB; HostDB:geneid_417213; -.
DR   eggNOG; ENOG502QUXQ; Eukaryota.
DR   InParanoid; Q5ZKK5; -.
DR   OrthoDB; 328077at2759; -.
DR   PhylomeDB; Q5ZKK5; -.
DR   PRO; PR:Q5ZKK5; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005813; C:centrosome; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0036126; C:sperm flagellum; ISS:UniProtKB.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:1902017; P:regulation of cilium assembly; IBA:GO_Central.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR026099; Odf2-rel.
DR   PANTHER; PTHR23162; PTHR23162; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Developmental protein; Differentiation; Flagellum; Microtubule;
KW   Reference proteome; Spermatogenesis.
FT   CHAIN           1..822
FT                   /note="Outer dense fiber protein 2"
FT                   /id="PRO_0000299461"
FT   REGION          26..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          113..418
FT                   /evidence="ECO:0000255"
FT   COILED          452..490
FT                   /evidence="ECO:0000255"
FT   COILED          516..796
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   822 AA;  95957 MW;  C3FF206849D88FFB CRC64;
     MKNRSSSPPL HVHVDENTPV HVHIKKGQKT TPAKCQQKHK QKMKGNTVNV RRAVQVKTKA
     PWMPPGKTSV LDSTYKWEGP THLLEITPPE SEKMMSVLRL SDLSTDEEDA VCCKMNEYER
     KIDSLMNVVG TLKNEAKLQK QEQRQQMTKR LLEEQKEELN EVTQELAESE HENTLLRRNI
     ERMREEKDLT MLQKKYLQHE KECLLSKLSE AERDGAAAAR EIHALKSTIE RLNVEKHMSS
     SDINMLTRQK ELLLQKLSTF EETNRTLREL LREQHERERD VQKILEKQGV LMKMLADSDA
     EKLQLQMRLQ DKEKEINNLA VQIQEEKEQA RTASELSKSL ESVRGHLQAQ LRHKEAENNR
     LTTQIRNLER SEAQHKAEVE CIKDQLKELR QKADRDKDAL KRALRAQKER AERSEECAGQ
     LAVQLAEKDS YVAEALSTLE SWRSRYNKVV KDKSDLELEM VTVNSRIADL LEQQATLEDK
     MREDRDALMD KLHQQTTETT SFRMENERLK ASVVPMEEKL NQAHVEVQQL KSSVRNYEDL
     IETYKSQVLK TRMEAADVAA KLEKCDNEKK ALKDEMNKEL ELARKQFQSQ LAELEKLPEI
     LRITETQLAE CQDQLQSYEK KNMDLSVMIA DLRQRIELQG DKMEMTRERY QSAQEEKKQL
     TLKAEELERK LETTSTQNIE FLQVIAKREE SIHQCQLRLE EKTRECSSLA RQLEMAIEDA
     KREVEQTRER ATSRERAAQS KVLDLETQLS RTKTELNQLR RNKEDAERRY ESRLQDLKDR
     LEQSESTNRS MQNYVQFLKS SYANVFADSA LLGSPGRSRS SP