ID   ODFP2_XENLA             Reviewed;         649 AA.
AC   Q5PQ23;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Outer dense fiber protein 2;
DE   AltName: Full=Cenexin;
DE   AltName: Full=Outer dense fiber of sperm tails protein 2;
GN   Name=odf2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Seems to be a major form of sperm tail outer dense fibers.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Self-associates. Associates with microtubules and forms a
CC       fibrillar structure partially linked to the microtubule network (By
CC       similarity). {ECO:0000250|UniProtKB:Q5BJF6}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250|UniProtKB:A3KGV1}. Cell projection,
CC       cilium {ECO:0000250|UniProtKB:A3KGV1}. Cytoplasm, cytoskeleton,
CC       microtubule organizing center, centrosome, centriole
CC       {ECO:0000250|UniProtKB:A3KGV1}. Cytoplasm, cytoskeleton, spindle pole
CC       {ECO:0000250|UniProtKB:A3KGV1}. Cell projection, cilium, flagellum
CC       {ECO:0000250|UniProtKB:A3KGV1}.
CC   -!- SIMILARITY: Belongs to the ODF2 family. {ECO:0000305}.
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DR   EMBL; BC087396; AAH87396.1; -; mRNA.
DR   RefSeq; NP_001088742.1; NM_001095273.1.
DR   AlphaFoldDB; Q5PQ23; -.
DR   SMR; Q5PQ23; -.
DR   DNASU; 496006; -.
DR   GeneID; 496006; -.
DR   CTD; 496006; -.
DR   Xenbase; XB-GENE-977569; odf2.L.
DR   OrthoDB; 328077at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 496006; Expressed in testis and 14 other tissues.
DR   GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0036126; C:sperm flagellum; ISS:UniProtKB.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR026099; Odf2-rel.
DR   PANTHER; PTHR23162; PTHR23162; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Developmental protein; Differentiation; Flagellum; Microtubule;
KW   Reference proteome; Spermatogenesis.
FT   CHAIN           1..649
FT                   /note="Outer dense fiber protein 2"
FT                   /id="PRO_0000299462"
FT   REGION          1..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          339..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          137..219
FT                   /evidence="ECO:0000255"
FT   COILED          247..426
FT                   /evidence="ECO:0000255"
FT   COILED          464..649
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   649 AA;  75494 MW;  B15755A0BFE376BF CRC64;
     MKNRSPSPPL HVHVDESTPV HVHIKKSSRP PAKTQQGAKL KKKGMGNLRR SATVKTKVPW
     IPPGKSSLRD AGLKWEGLTH RLDITPPDTE RMFSALRMSD LSTDEEEMKR SKMNSYEEKI
     ATLMSEMGTL KHELELQKRE KYLGKCEEQL AASKRLLEAQ QEELAEVSQE LVETENENVW
     LKRSLDRIQE EKGLSILQKQ QLQEEKAHLL AKLLEAETDG AEAAKQVTLL SDTIQRLKHE
     KRMTSTDINL LTRQKELLLQ KLNTFEDTNR SLRTLLREQH RQETETYRLM EQKEMLLKKL
     SDADTEKMHL QLKLHEQEEK VEDLLAQLKT EKDLSKTASE VSKSIESTKA HLQGQLRTRE
     AENNRLSVQI RNLERNEAHQ KEEIVKLMEQ LTELKQKVDS EKEALKKSVR AQKQRAERSE
     ETLEMLNRQL VGNDSELAKA LSSAETWRSR YNKLMKESSQ HEEEVAVLSN RLKGLLGESH
     GIEERGRLER DSLLEKLHQQ TTENTCLRLE HEKLKASLTT VEEKLSLAQS EVQQLKNSLR
     QYEGLVDTYK EQLQKSRQEA NSISLQLEMS EKENKNIKED MNLELEQMRR KFQNRLSELE
     HLPEILKSTE LDLQECHQQL RSYEQKSSEL SSTISDLRTR VRNWRNCAL