ID   ODFP4_RAT               Reviewed;         290 AA.
AC   Q6AXT9;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Outer dense fiber protein 4;
DE   AltName: Full=Outer dense fiber of sperm tails protein 4;
GN   Name=Odf4;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Component of the outer dense fibers (ODF) of spermatozoa
CC       which could be involved in sperm tail structure, sperm movement and
CC       general organization of cellular cytoskeleton. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC079319; AAH79319.1; -; mRNA.
DR   RefSeq; NP_001007671.1; NM_001007670.1.
DR   AlphaFoldDB; Q6AXT9; -.
DR   STRING; 10116.ENSRNOP00000005667; -.
DR   PaxDb; Q6AXT9; -.
DR   GeneID; 303236; -.
DR   KEGG; rno:303236; -.
DR   UCSC; RGD:1359332; rat.
DR   CTD; 146852; -.
DR   RGD; 1359332; Odf4.
DR   VEuPathDB; HostDB:ENSRNOG00000004225; -.
DR   eggNOG; ENOG502SXVG; Eukaryota.
DR   HOGENOM; CLU_062754_0_0_1; -.
DR   InParanoid; Q6AXT9; -.
DR   OMA; RWPVDVS; -.
DR   OrthoDB; 1432634at2759; -.
DR   PhylomeDB; Q6AXT9; -.
DR   PRO; PR:Q6AXT9; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000004225; Expressed in testis and 2 other tissues.
DR   Genevisible; Q6AXT9; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031514; C:motile cilium; ISO:RGD.
DR   GO; GO:0001520; C:outer dense fiber; ISO:RGD.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR   Pfam; PF00822; PMP22_Claudin; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Differentiation; Membrane; Phosphoprotein;
KW   Reference proteome; Spermatogenesis; Transmembrane; Transmembrane helix.
FT   CHAIN           1..290
FT                   /note="Outer dense fiber protein 4"
FT                   /id="PRO_0000304724"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          262..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         28
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8VI88"
SQ   SEQUENCE   290 AA;  33146 MW;  4BC2A51749650BB7 CRC64;
     MESDLTVEES ETIKTRSRRP LTEHRRHSLL PLQWKLAHSS RWMAQVVASE FSLLAFLLLL
     LMVFSKKWLY PSKSRFHQRY PQNITKRVYT SIHSMSTGLL YICISKSCLS SDNEEDNFKM
     WTIHPAFGVA KISFILAVGL GFVLTVWLHL PYLPCLQRMP FFGLIGIILS FCEVTLIFLT
     LLLFPVNLWI YELKKNISVP IGWSYFIGWL VLILYLTCGI LCYLNHKNFW SLIMSSSSIN
     ATCSSSVPVS LMNTSQISKS QADILDPTQD DQKPLSSDNI ALPPNPDTTD