ID   ODHI_CORJK              Reviewed;         144 AA.
AC   Q4JVU0;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Oxoglutarate dehydrogenase inhibitor;
GN   Name=odhI; OrderedLocusNames=jk0903;
OS   Corynebacterium jeikeium (strain K411).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=306537;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K411;
RX   PubMed=15968079; DOI=10.1128/jb.187.13.4671-4682.2005;
RA   Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A.,
RA   Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F.,
RA   Rupp O., Schneiker S., Viehoever P., Puehler A.;
RT   "Complete genome sequence and analysis of the multiresistant nosocomial
RT   pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the
RT   human skin flora.";
RL   J. Bacteriol. 187:4671-4682(2005).
CC   -!- FUNCTION: An essential component of the PknG signaling pathway. When
CC       unphosphorylated, it inhibits the activity of 2-oxoglutarate
CC       dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate
CC       dehydrogenase (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
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DR   EMBL; CR931997; CAI37067.1; -; Genomic_DNA.
DR   RefSeq; WP_005294594.1; NC_007164.1.
DR   AlphaFoldDB; Q4JVU0; -.
DR   SMR; Q4JVU0; -.
DR   STRING; 306537.jk0903; -.
DR   EnsemblBacteria; CAI37067; CAI37067; jk0903.
DR   KEGG; cjk:jk0903; -.
DR   eggNOG; COG1716; Bacteria.
DR   HOGENOM; CLU_108862_1_0_11; -.
DR   OMA; IGKFRLT; -.
DR   OrthoDB; 1632705at2; -.
DR   Proteomes; UP000000545; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd00060; FHA; 1.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   Pfam; PF00498; FHA; 1.
DR   SMART; SM00240; FHA; 1.
DR   SUPFAM; SSF49879; SSF49879; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Phosphoprotein; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..144
FT                   /note="Oxoglutarate dehydrogenase inhibitor"
FT                   /id="PRO_0000272965"
FT   DOMAIN          68..117
FT                   /note="FHA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00086"
FT   MOD_RES         14
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   144 AA;  15536 MW;  88517200FC3946E5 CRC64;
     MSDNTGVPEA SVETTSVFRA DLLKEMESGS QHDASPAGVE GLPEGSALLV VKRGPNAGSR
     FLLDQETTAA GRHPDSDIFL DDVTVSRRHA EFRRNGDQYE VVDVGSLNGT YVNREPKNSS
     VLSNGDEIQI GKFRLVFLNG SKEA