ID   ODH_HALDH               Reviewed;         405 AA.
AC   Q8N0N9;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Opine dehydrogenase {ECO:0000303|PubMed:15565272};
DE            EC=1.5.1.- {ECO:0000303|PubMed:15565272};
GN   Name=tadh {ECO:0000312|EMBL:BAB92088.1};
OS   Haliotis discus hannai (Japanese abalone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Vetigastropoda; Lepetellida; Haliotoidea; Haliotidae; Haliotis.
OX   NCBI_TaxID=42344;
RN   [1] {ECO:0000312|EMBL:BAB92088.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Muscle {ECO:0000269|PubMed:15565272};
RX   PubMed=15565272; DOI=10.1007/s10126-004-2700-6;
RA   Kimura T., Nakano T., Yamaguchi T., Sato M., Ogawa T., Muramoto K.,
RA   Yokoyama T., Kan-No N., Nagahisa E., Janssen F., Grieshaber M.K.;
RT   "Complementary DNA cloning and molecular evolution of opine dehydrogenases
RT   in some marine invertebrates.";
RL   Mar. Biotechnol. 6:493-502(2004).
CC   -!- SIMILARITY: Belongs to the lysopine/nopaline/octopine/opine/vitopine
CC       dehydrogenases family. {ECO:0000255}.
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DR   EMBL; AB085184; BAB92088.1; -; mRNA.
DR   AlphaFoldDB; Q8N0N9; -.
DR   SMR; Q8N0N9; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR013332; KPR_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003421; Opine_DH.
DR   Pfam; PF02558; ApbA; 1.
DR   Pfam; PF02317; Octopine_DH; 1.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   NAD; Oxidoreductase.
FT   CHAIN           1..405
FT                   /note="Opine dehydrogenase"
FT                   /id="PRO_0000413661"
SQ   SEQUENCE   405 AA;  45065 MW;  9D57405A29097916 CRC64;
     MTKKITVLVC GGGNGAHVTA GLAASRDDIE TRVLTTFADE AERWTNIMKE NDLRITVDEG
     DIKSGESVDF KVKLNCITKD PSKAVPGADV IIFTVPAFAH QSYLEAIEPY IQPNTTIVGM
     PGQPGFEFQV FDVLKDKAKQ CVIMSFESLP WACRIAEFGK FVQILMVKVN LMGCLIRGQS
     KPSYDPMEAV QRVMGKAPIL TQANNYIEPI LATKSIIHPP IMYGKWKDWD GKPIEEKPLF
     YQGLDEEQAR YLGGISDELV ATAKAIAAQK PEVDLSGVLH LYDWYLRDHK PYIKDTTSLL
     TVLQTDTAYD GLVHPMKETE DGKFVPDFRY RYLTEDVPNG LVVTKGLAQI AGVPTPYHDE
     VIAWCQKQLG KEIIVGDELK GKDIGSTRCP QRYGINTMDA LVNIM