ODR10_CAEBR
ID ODR10_CAEBR Reviewed; 342 AA.
AC A8XC92; C3U4X6;
DT 09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Serpentine receptor class r-10 {ECO:0000250|UniProtKB:Q18807};
DE AltName: Full=Odorant response abnormal protein 10 {ECO:0000250|UniProtKB:Q18807};
DE AltName: Full=Olfactory receptor 10 {ECO:0000250|UniProtKB:Q18807};
GN Name=odr-10 {ECO:0000312|EMBL:ACQ44053.1}; ORFNames=CBG10912;
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238;
RN [1] {ECO:0000312|EMBL:ACQ44053.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=DH1300 {ECO:0000312|EMBL:ACQ44054.1},
RC HK104 {ECO:0000312|EMBL:ACQ44052.1}, HK105 {ECO:0000312|EMBL:ACQ44051.1},
RC and VT847 {ECO:0000312|EMBL:ACQ44053.1};
RX PubMed=19001295; DOI=10.1534/genetics.107.082651;
RA Jovelin R., Dunham J.P., Sung F.S., Phillips P.C.;
RT "High nucleotide divergence in developmental regulatory genes contrasts
RT with the structural elements of olfactory pathways in caenorhabditis.";
RL Genetics 181:1387-1397(2009).
RN [2] {ECO:0000312|EMBL:CAP30190.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16;
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R.M., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- FUNCTION: An odorant receptor which affects chemotaxis to the volatile
CC odorant diacetyl. Specifies AWA neuronal cell fate via the odr-7
CC pathway (By similarity). {ECO:0000250|UniProtKB:Q18807}.
CC -!- SUBUNIT: Interacts with odr-4.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium membrane
CC {ECO:0000250|UniProtKB:Q18807, ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000250|UniProtKB:Q18807, ECO:0000255}.
CC -!- SIMILARITY: Belongs to the nematode receptor-like protein str family.
CC {ECO:0000255}.
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DR EMBL; FJ455661; ACQ44051.1; -; Genomic_DNA.
DR EMBL; FJ455662; ACQ44052.1; -; Genomic_DNA.
DR EMBL; FJ455663; ACQ44053.1; -; Genomic_DNA.
DR EMBL; FJ455664; ACQ44054.1; -; Genomic_DNA.
DR EMBL; HE601482; CAP30190.2; -; Genomic_DNA.
DR AlphaFoldDB; A8XC92; -.
DR STRING; 6238.CBG10912; -.
DR EnsemblMetazoa; CBG10912.1; CBG10912.1; WBGene00032158.
DR WormBase; CBG10912; CBP28942; WBGene00032158; Cbr-odr-10.
DR eggNOG; ENOG502TFTY; Eukaryota.
DR HOGENOM; CLU_036335_2_1_1; -.
DR InParanoid; A8XC92; -.
DR OMA; MWASVSY; -.
DR OrthoDB; 954390at2759; -.
DR Proteomes; UP000008549; Chromosome X.
DR GO; GO:0060170; C:ciliary membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030425; C:dendrite; IEA:EnsemblMetazoa.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0043025; C:neuronal cell body; IEA:EnsemblMetazoa.
DR GO; GO:0097730; C:non-motile cilium; IEA:EnsemblMetazoa.
DR GO; GO:1990075; C:periciliary membrane compartment; IEA:EnsemblMetazoa.
DR GO; GO:0038022; F:G protein-coupled olfactory receptor activity; IBA:GO_Central.
DR GO; GO:0001965; F:G-protein alpha-subunit binding; IEA:EnsemblMetazoa.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0042048; P:olfactory behavior; IBA:GO_Central.
DR GO; GO:0050918; P:positive chemotaxis; IEA:EnsemblMetazoa.
DR InterPro; IPR019428; 7TM_GPCR_serpentine_rcpt_Str.
DR Pfam; PF10326; 7TM_GPCR_Str; 1.
PE 3: Inferred from homology;
KW Cell membrane; Cell projection; Chemotaxis; Cilium; Glycoprotein; Membrane;
KW Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..342
FT /note="Serpentine receptor class r-10"
FT /id="PRO_0000391383"
FT TOPO_DOM 1..11
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 12..32
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 33..38
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 60..92
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 93..113
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 114..131
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 132..152
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 153..202
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 203..223
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 224..257
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 258..278
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 279..285
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 286..306
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 307..342
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 71
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 83
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 179
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 226
FT /note="L -> S (in Ref. 1; ACQ44051/ACQ44052)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 342 AA; 39671 MW; AC3318DE7333300A CRC64;
MTGELWLTLV DTADIVGFSM TFCVNIVLLF LLKNRGKNLG TYKHLMAFFS VFSIFYAIIE
SILRPIMHIE NATFFLISRK RFNYSTRLGK INSAFYCACF ATSFVVSGVH FVYRFFASCK
PHLLRSFNMP YLLLWPLGCS IPVMMWASVS YFLYPDTAFT EAAVTNVLNT HYHSIKKDNV
SYIAYVYYQY DENGVRYVYL KNLLGCFVHY FVMSATFVVM FICGYLTWKT MRKHKTASDR
TRQLQKQLFK ALVLQTLIPT IFMYAPTGVM FIAPFFSINL NANANFIVFC SFLYPGLDPL
ILILIIRDFR QTVFKFFCLR KKNSVDESRS TTRANMSQVA TH
