OEP39_ARATH
ID OEP39_ARATH Reviewed; 362 AA.
AC Q5PP51; Q9LXP7;
DT 08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Outer envelope protein 39, chloroplastic {ECO:0000305};
GN Name=P39 {ECO:0000303|PubMed:29758131};
GN OrderedLocusNames=At3g44160 {ECO:0000312|Araport:AT3G44160};
GN ORFNames=F26G5_110 {ECO:0000312|EMBL:CAB88424.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP TISSUE SPECIFICITY.
RX PubMed=25608613; DOI=10.1007/s10265-014-0693-4;
RA Nicolaisen K., Missbach S., Hsueh Y.C., Ertel F., Fulgosi H., Sommer M.S.,
RA Schleiff E.;
RT "The Omp85-type outer membrane protein p36 of Arabidopsis thaliana evolved
RT by recent gene duplication.";
RL J. Plant Res. 128:317-325(2015).
RN [5]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=25401771; DOI=10.1002/prot.24725;
RA Hsueh Y.C., Flinner N., Gross L.E., Haarmann R., Mirus O., Sommer M.S.,
RA Schleiff E.;
RT "Chloroplast outer envelope protein P39 in Arabidopsis thaliana belongs to
RT the Omp85 protein family.";
RL Proteins 85:1391-1401(2017).
RN [6]
RP FUNCTION, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=29758131; DOI=10.1111/plb.12839;
RA Hsueh Y.C., Nicolaisen K., Gross L.E., Noethen J., Schauer N., Vojta L.,
RA Ertel F., Koch I., Ladig R., Fulgosi H., Fernie A.R., Schleiff E.;
RT "The outer membrane Omp85-like protein P39 influences metabolic homeostasis
RT in mature Arabidopsis thaliana.";
RL Plant Biol. 20:825-833(2018).
CC -!- FUNCTION: Beta-barrel pore-forming protein which possesses voltage-
CC dependent channel activity (PubMed:25401771). Required for proper
CC plastid development (PubMed:29758131). Involved in the maintenance of
CC metabolic homeostasis of full-grown plants (PubMed:29758131).
CC {ECO:0000269|PubMed:25401771, ECO:0000269|PubMed:29758131}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast outer membrane
CC {ECO:0000269|PubMed:25401771}.
CC -!- TISSUE SPECIFICITY: Expressed in germinating seeds (PubMed:25608613).
CC Expressed in the vasculature of roots, cotyledons and leaves
CC (PubMed:25608613, PubMed:29758131). {ECO:0000269|PubMed:25608613,
CC ECO:0000269|PubMed:29758131}.
CC -!- DISRUPTION PHENOTYPE: Stunted growth, pale-green leaves, altered
CC plastid structures in leaves, altered photosynthesis activity, and
CC reduced accumulation of starch in leaf chloroplasts.
CC {ECO:0000269|PubMed:29758131}.
CC -!- SIMILARITY: Belongs to the OEP80 (TC 1.B.33.2) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB88424.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL353814; CAB88424.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77870.1; -; Genomic_DNA.
DR EMBL; BT020246; AAV74240.1; -; mRNA.
DR EMBL; BT021139; AAX22274.1; -; mRNA.
DR PIR; T49132; T49132.
DR RefSeq; NP_190002.2; NM_114284.4.
DR AlphaFoldDB; Q5PP51; -.
DR STRING; 3702.AT3G44160.1; -.
DR PaxDb; Q5PP51; -.
DR PRIDE; Q5PP51; -.
DR ProteomicsDB; 175422; -.
DR EnsemblPlants; AT3G44160.1; AT3G44160.1; AT3G44160.
DR GeneID; 823537; -.
DR Gramene; AT3G44160.1; AT3G44160.1; AT3G44160.
DR KEGG; ath:AT3G44160; -.
DR Araport; AT3G44160; -.
DR TAIR; locus:2081423; AT3G44160.
DR eggNOG; ENOG502QT7K; Eukaryota.
DR HOGENOM; CLU_078932_0_0_1; -.
DR InParanoid; Q5PP51; -.
DR OMA; FTHKLCT; -.
DR OrthoDB; 265672at2759; -.
DR PhylomeDB; Q5PP51; -.
DR PRO; PR:Q5PP51; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q5PP51; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0009707; C:chloroplast outer membrane; IDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0001401; C:SAM complex; IBA:GO_Central.
DR GO; GO:0015267; F:channel activity; IDA:TAIR.
DR GO; GO:0009658; P:chloroplast organization; IBA:GO_Central.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IBA:GO_Central.
DR GO; GO:0045040; P:protein insertion into mitochondrial outer membrane; IBA:GO_Central.
DR GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR InterPro; IPR000184; Bac_surfAg_D15.
DR InterPro; IPR039910; D15-like.
DR PANTHER; PTHR12815; PTHR12815; 1.
DR Pfam; PF01103; Omp85; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Growth regulation; Membrane; Plastid; Plastid outer membrane;
KW Reference proteome.
FT CHAIN 1..362
FT /note="Outer envelope protein 39, chloroplastic"
FT /id="PRO_0000446978"
SQ SEQUENCE 362 AA; 39010 MW; 383B1596A41F660A CRC64;
MGAQKSIHAG RAKIDVNVDF THKLCTSLMF PAFRDTSSPL SLVIGSLCIK HPNLFGGSEK
LDVSWDKGLY DSNVLVAFRR PRPEWRPQQC FFIQHSLSPE IGVHGTPVDN FSRSGSGGVN
LSKLALGLDL SEPASSKWSS TTSIKFEHVR PINDDGRAIT RDLDGFPITC SGNTHDSMVV
LKQESRFAKA TDQGLSHFSM QIEQGIPVVS KWLIFNRFKF VASKGVRFGP AFLLASLTGG
SIVGDMAPYQ AFAIGGLGSV RGYGEGAVGS GRSCLVANTE LALPLNKMTE GTIFLDCGTD
LGSSRLVPGN PSMRQGKPGF GYGFGYGLRF KSPLGHLQVD YAINAFNQKT LYFGVTNLAS
ST
