OFP14_ARATH
ID OFP14_ARATH Reviewed; 294 AA.
AC Q9S7T5;
DT 09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Transcription repressor OFP14;
DE AltName: Full=Ovate family protein 14;
DE Short=AtOFP14;
GN Name=OFP14; OrderedLocusNames=At1g79960; ORFNames=F18B13.4, F19K16.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP INTERACTION WITH KNAT2 AND KNAT3.
RX PubMed=15781858; DOI=10.1073/pnas.0501181102;
RA Hackbusch J., Richter K., Muller J., Salamini F., Uhrig J.F.;
RT "A central role of Arabidopsis thaliana ovate family proteins in networking
RT and subcellular localization of 3-aa loop extension homeodomain proteins.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:4908-4912(2005).
RN [5]
RP FUNCTION, TISSUE SPECIFICITY, AND GENE FAMILY.
RX PubMed=21886836; DOI=10.1371/journal.pone.0023896;
RA Wang S., Chang Y., Guo J., Zeng Q., Ellis B.E., Chen J.G.;
RT "Arabidopsis ovate family proteins, a novel transcriptional repressor
RT family, control multiple aspects of plant growth and development.";
RL PLoS ONE 6:E23896-E23896(2011).
CC -!- FUNCTION: Transcriptional repressor that may regulate multiple aspects
CC of plant growth and development through the regulation of BEL1-LIKE
CC (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
CC {ECO:0000269|PubMed:21886836}.
CC -!- SUBUNIT: Interacts with KNAT2 and KNAT3. {ECO:0000269|PubMed:15781858}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, rosette and cauline leaves,
CC shoots, stems, flower buds and siliques. {ECO:0000269|PubMed:21886836}.
CC -!- MISCELLANEOUS: Plants over-expressing OFP14 have no visible phenotype.
CC {ECO:0000305|PubMed:21886836}.
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DR EMBL; AC009322; AAD55464.1; -; Genomic_DNA.
DR EMBL; AC011717; AAG52238.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36334.1; -; Genomic_DNA.
DR EMBL; DQ056520; AAY78676.1; -; mRNA.
DR PIR; H96830; H96830.
DR RefSeq; NP_178114.1; NM_106645.2.
DR AlphaFoldDB; Q9S7T5; -.
DR BioGRID; 29554; 2.
DR IntAct; Q9S7T5; 2.
DR STRING; 3702.AT1G79960.1; -.
DR PaxDb; Q9S7T5; -.
DR PRIDE; Q9S7T5; -.
DR ProteomicsDB; 238924; -.
DR EnsemblPlants; AT1G79960.1; AT1G79960.1; AT1G79960.
DR GeneID; 844336; -.
DR Gramene; AT1G79960.1; AT1G79960.1; AT1G79960.
DR KEGG; ath:AT1G79960; -.
DR Araport; AT1G79960; -.
DR TAIR; locus:2016344; AT1G79960.
DR eggNOG; ENOG502RXZT; Eukaryota.
DR HOGENOM; CLU_069722_0_0_1; -.
DR InParanoid; Q9S7T5; -.
DR OMA; CIRDDQE; -.
DR OrthoDB; 1454476at2759; -.
DR PhylomeDB; Q9S7T5; -.
DR PRO; PR:Q9S7T5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9S7T5; differential.
DR Genevisible; Q9S7T5; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR InterPro; IPR038933; Ovate.
DR InterPro; IPR006458; Ovate_C.
DR PANTHER; PTHR33057; PTHR33057; 1.
DR Pfam; PF04844; Ovate; 1.
DR TIGRFAMs; TIGR01568; A_thal_3678; 1.
DR PROSITE; PS51754; OVATE; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..294
FT /note="Transcription repressor OFP14"
FT /id="PRO_0000429683"
FT DOMAIN 195..259
FT /note="OVATE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01090"
FT REGION 49..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 96..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 294 AA; 34357 MW; 4C0A20F4065721EF CRC64;
MPNPLQKSLH GYLSKIKKET GKLQLSSSHS FSSSKNWVLG KHPKKLSFSF KHRRRSSKTR
FSKEEPVYHQ DSAHAATLSD IDRFLEENFK SLCIRDDQED DQHQARVTKN KEKRESSSDD
SDDDDDDDDY RHRFERTWGH AVYDSPKQPP DLLRTERLSP PPGSSEGRPS METTSTSSER
QSRSTLVLPE NCIAVLRYTD EPQEDFRQSM VEMMESKLGM RESEVDWDLM EELLFCYLDL
NDKKSHKFIL SAFVDLIIAL REKEKRITRK GHVRSLSTRA ARDRLRKRMI MSDN
